Results 51 to 60 of about 512,021 (296)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Digital decoder for phase-delay coded data [PDF]
, 1971 Coded or modulated digital data converts to nonreturn to zero /NRZ/ data. Technique includes logic implementation and pertinent timing diagrams. Demodulation to NRZ facilitates digital logic operations on incoming data.
Lewin, J.
core +1 more source
Segmented optical transmitter comprising a CMOS driver array and an InP IQ-MZM for advanced modulation formats [PDF]
, 2017 Segmented Mach-Zehnder modulators are promising solutions to generate complex modulation schemes in the migration towards optical links with a higher-spectral efficiency.
Aimone, Alessandro +12 more
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Single Photon Compressive Imaging Based on Digital Grayscale Modulation Method
Photonic Sensors, 2020 In single-pixel imaging or computational ghost imaging, the measurement matrix has a great impact on the performance of the imaging system, because it involves modulation of the optical signal and image reconstruction.
Chenglong Yuan +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Research on Influencing Factors of Digital Signal Modulation Recognition
Advances in Electrical and Computer Engineering, 2019 In the real environment, modulation recognition has low classification recognition rate under low SNR and is affected by many factors such as symbol rate, frequency offset and adjacent channel crosstalk. Based on the combination of high-order cumulants
WANG, J., DU, H.
doaj +1 more source
Maximizing the Bandwidth Efficiency of the CMS Tracker Analog Optical Links
, 2005 The feasibility of achieving faster data transmission using advanced digital modulation techniques over the current CMS Tracker analog optical link is explored.
Axer, Markus +6 more
core +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source