Results 51 to 60 of about 38,051,230 (246)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Research on Influencing Factors of Digital Signal Modulation Recognition

open access: yesAdvances in Electrical and Computer Engineering, 2019
In the real environment, modulation recognition has low classification recognition rate under low SNR and is affected by many factors such as symbol rate, frequency offset and adjacent channel crosstalk. Based on the combination of high-order cumulants
WANG, J., DU, H.
doaj   +1 more source

Single Photon Compressive Imaging Based on Digital Grayscale Modulation Method

open access: yesPhotonic Sensors, 2020
In single-pixel imaging or computational ghost imaging, the measurement matrix has a great impact on the performance of the imaging system, because it involves modulation of the optical signal and image reconstruction.
Chenglong Yuan   +4 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Gaussian Q Function Approximation in Wireless Communication System’s Design: A Gradient-Based Optimization Approach

open access: yesIEEE Access
This paper proposes a novel iterative gradient-based optimization approach aimed at achieving more precise and streamlined approximations for the Gaussian Q function—an essential element in communication system’s design.
Leuva Bhumika Ranchhodbhai   +1 more
doaj   +1 more source

Data-Aided Carrier Recovery with QPSK Modulation

open access: yesBuletinul Ştiinţific al Academiei Trupelor de Uscat, 2019
Digital communication has proven to be the most efficient method of data transmission especially where long distances are involved. This led to the invention of more sophisticated methods of communication ranging from mobile handset communication to more
Al-Rawi Muhanned
doaj   +1 more source

Optimum Mode-Switching-Assisted Constant-Power Single- and Multicarrier Adaptive Modulation

open access: yes, 2003
A set of optimum mode-switching levels is derived for a generic constant-power adaptive-modulation scheme based on a closed-form expression of the average bit error ratio (BER) and the average bits-per-symbol (BPS) throughput of the adaptive-modulation ...
Choi, B.J., Hanzo, L.
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

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