Results 191 to 200 of about 35,296,567 (265)

Methodology and enrollment findings of the Beijing adult dry eye cohort study. [PDF]

Front Med (Lausanne)
Cao K, Shi R, Tian L, Jie Y.
europepmc   +1 more source

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

Bridging the digital divide: student-led literacy initiatives in diabetes management. [PDF]

Front Clin Diabetes Healthc
Moyano PA, Raddaoui M, de Barros Coscelli Ferraz A, Martiniano Porfírio GJ, Campos LA, Baltatu OC.   +5 more
europepmc   +1 more source

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source

The impact of non-native trees on galling and herbivory in New York City across space and time. [PDF]

Oecologia
Engel LD, Smith A, Cardenas I, Abdulkarem D, Vasquez CC, Hekkala E, Herstoff EM, Tessler M.   +7 more
europepmc   +1 more source

Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop

Advanced Science, EarlyView.
In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang, Hongjie Gao, Bifei Zhang, Xuetian Li, Ding Li, Aihua Cao, Fengyin Sun   +6 more
wiley   +1 more source

Mortality trends of comorbid viral hepatitis C and psychoactive substance use disorders in the United States: Insights from CDC WONDER, 1999-2023. [PDF]

Medicine (Baltimore)
Fatima M, Faisal M, Shafee WF, Iqbal M, Iqbal M, Furqan N, Khalid M, Usmani UA, Fatima S, Noor R.   +9 more
europepmc   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Mycorrhizal strategy of non-native plants varies with biome and disturbance. [PDF]

Nat Ecol Evol
Cazzaniga SG, Lauber T, van den Hoogen J, Beaury EM, Bueno CG, Bever JD, Damasceno G, Catford J, Lenoir J, Martin A, Mori AS, Novakovskiy A, Gutiérrez AG, González-Robles A, de Gasper AL, Moles A, Stanisci A, Csecserits A, Jentsch A, Kuzemko A, Perea AJ, Nerlekar A, Munje A, Güler B, Jiménez-Alfaro B, Hérault B, Pinho BX, Baraloto C, Rossi C, Hending D, Laughlin DC, Rogers D, Schellenberger Costa D, Thakur D, Uogintas D, Chacón-Madrigal E, Alvarez-Davila E, Weiher E, Thomas E, Gonçalves F, Rodrigues F, Sabatini FM, Schurr FM, Essl F, Zizka G, Bonari G, Swacha G, Chen HYH, Bruelheide H, Ford H, Wang HF, Biurrun I, Aubin I, Dembicz I, Willie J, Altman J, Svenning JC, Lichstein JW, Moeslund JE, Dolezal J, Cornelissen JHC, Hunter J, Messier J, Dengler J, Homeier J, Orwin KH, Korznikov K, Van Meerbeek K, Macía MJ, Schmidt M, Varricchione M, Carlucci MB, Spasojevic M, Giorgis MA, Chytrý M, El-Sheikh MA, Hatim MZ, Kraft NJB, Mohanbabu N, Phillips OL, Reich PB, Pielech R, Arasa-Gisbert R, Guarino R, Testolin R, Tarifa R, Mukul SA, Phartyal SS, Schmitt S, Haider S, Dziuba T, Domingues T, Liu U, Golub V, Silva V, Fontana V, Vandvik V, Kissling WD, Stančić Z, Winter M, Crowther TW, Delavaux CS.   +101 more
europepmc   +1 more source

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

Advanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou, Qiong Xue, Su‐Xuan Hou, Ke‐Yao Zhang, Wei‐Tong Pan, Ting‐Ting Zeng, Yu‐Ge Wang, Daqing Ma, Chenguang Zhao, Pan‐Miao Liu, Jian‐Jun Yang   +10 more
wiley   +1 more source