Results 31 to 40 of about 43,181,198 (233)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
Highly integrated automated γ spectrometer
四川大学学报. 自然科学版, 2021 With respect to the need for online γ-ray monitoring in the containment of nuclear reactors, a γ spectrometer with high integration, low power consumption, high energy resolution, long endurance and automatic measurement is designed in this paper.
CHEN Qi +4 more
doaj
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Application of lightweight neural network models for nuclear pulse parameter prediction
He jishuBackgroundIn nuclear radiation measurement, pulse distortion is inevitable due to the interference of the measurement system itself and the measurement environment.
TANG Lin +3 more
doaj +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
FEBS Open Bio, EarlyView.Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Flat-topped cusp-like shaper algorithm based on the unfolding-synthesis technique
He jishuBackgroundThe unfolding-synthesis technique is commonly used in digital pulse processing systems for nuclear radiation measurements.PurposeThis study aims to propose a novel flat-topped widened peak-shaping algorithm based on the pulse unfolding ...
LAN Jimei +5 more
doaj +1 more source
Nuclear Pulse Height Measurement Using FPGA Techniques [PDF]
, 2010 [[abstract]]The present work is to use FPGAs as a digital processor for pulse height measurement. A digital periodic triangle signal is generated by an up-down counter with a positive edge trigger and followed by a synthesizable digital to analog ...
P.C. Tsao;H.P. Chou
core +1 more source
Advanced Engineering Materials, EarlyView.This article investigates the dependence of the properties on the manufacturing orientation in the form of the inclination angle to the build plate of LPBF‐fabricated NiTi rods with a diameter of 150–220 µm. Metallographic, chemical, thermal, and mechanical characterization show behavior under identical manufacturing conditions that ranges from ...
Sandra Herzig +2 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.The present work reports the microstructural, mechanical, and texture evolution of a dissimilar combination laser‐welded maraging steel with 4340 steel. This is important for aerospace applications. The demand for dissimilar welding is growing rapidly with the requirement of efficient and durable joints.
Bharat Behl +3 more
wiley +1 more source