Results 31 to 40 of about 556,516 (266)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The effects of digitalization on production
How does digitalization transform the macroeconomic production function? Using a model where firms can choose their technology, we find that sectors with more digital capital exhibit a higher elasticity of substitution between value added and intermediate inputs and between capital and labor.
Tryphonides, Andreas +3 more
openaire +2 more sources
The technological advances in additive manufacturing, particularly laser based directed energy deposition (DED), revolutionized the production of complex metal components. Despite this progress, the oriented heat flux and several reheating thermal cycles
Clemens Johannes Müller +4 more
doaj +1 more source
Forms of Remuneration for Free Software Production: A Reducible Complexity
How producers of free digital goods can be compensated for their labour is a major topic of debate and controversy in Free Software and related fields. This paper analytically disentangles the multiple modes of remuneration in operation in Free Software ...
Irzik Emrah
doaj +1 more source
ADAPTIVE TEXTURE SYNTHESIS FOR LARGE SCALE CITY MODELING [PDF]
Large scale city models textured with aerial images are well suited for bird-eye navigation but generally the image resolution does not allow pedestrian navigation.
G. Despine, T. Colleu
doaj +1 more source
A generic well-defined methodology for the construction and operation of dynamic process models of discrete industrial systems following a number of well-defined steps is introduced.
George Tsinarakis +2 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
RAY-BASED DETECTION OF OPENINGS IN URBAN AREAS USING MOBILE LIDAR DATA [PDF]
The detection of openings like windows or doors is of great interest in the field of urban modeling. Mobile LIDAR data provides valuable 3D information for that purpose.
T. Colleu, S. Benitez
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Instruments and materials for digital manufacturing in architecture
The article describes tools and materials available today for digital manufacturing in architecture, offering a wide overview of 3D printing techniques and how it could revolutionize the construction world with important come backs and not only technical
Cesare Sposito, Francesca Scalisi
doaj +1 more source

