Results 51 to 60 of about 39,314,757 (302)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Intermediate Frequency Digital Receiver Based on Multi-FPGA System

Journal of Electrical and Computer Engineering, 2016
Aiming at high-cost, large-size, and inflexibility problems of traditional analog intermediate frequency receiver in the aerospace telemetry, tracking, and command (TTC) system, we have proposed a new intermediate frequency (IF) digital receiver based on
Chengchang Zhang, Lihong Zhang
doaj   +1 more source

TRUST approach to software defined radio: RF considerations [PDF]

, 2000
The design of the RF component of a Software Defined Radio (SDR) is a challenging task. This paper sets out to examine the important issues concerning the design of both the transmitter and the receiver.
Macleod, JR, Jennings, D, Diaz, F, Gulobicic, Z, Warr, PA, Garcia, JA, Beach, MA, Alonso, J   +7 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Design of multi-channel test system based on JTAG interface

Dianzi Jishu Yingyong
The system is designed to realize the automatic acquisition and analysis of radar digital receivers. The digital IQ data is collected and stored by using the JTAG interface of the circuit and the SignalTap function of Quartus software.
Yang Jingsheng
doaj   +1 more source

System Concept of a Compact Multi-Antenna GNSS Receiver [PDF]

, 2012
This paper presents the conceptual design of a compact 2x2 array receiver for GNSS applications. Besides mere miniaturization, the goal of this work is also investigation on novel techniques for coping with the strong mutual coupling imposed in ...
Hein, Matthias, Kappen, Götz Caspar, Irteza, Safwat, Stephan, Ralf, Hein, M. A., Antreich, Felix, Khan, M. A., Sgammini, Matteo, Kappen, Götz, Kurz, Lothar, Basta, Nikola, Caizzone, Stefano, Dreher, A., Noll, Tobias G., Irteza, S., Richter, Andre, Dreher, Achim, Schäfer, Eric, Stephan, R., Schafer, E., Khan, Muhammad A., Richter, A.   +21 more
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Investigation of Offset Recovery Algorithms for High-Performance Bluetooth Receivers

, 2005
Research has shown that significant degradation in performance can occur even when operating within the limits for carrier frequency and modulation index offsets permitted by the Bluetooth standard.
Tibenderana, C, Weiss, S, Tibenderana, C., Weiss, S.   +3 more
core   +1 more source

Assessing the effect of DS-CDMA chip rate on RAKE branch statistics using a ray-tracing propagation model [PDF]

, 1994
An important improvement in the performance of CDMA and other wideband digital communication systems can be achieved using a RAKE receiver architecture and diversity combining of its branches. The paper presents an analysis of RAKE branch statistics as a
Anderson, HR, McGeehan, JP, H.R. Anderson, J.P. McGeehan   +3 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source