Results 31 to 40 of about 1,285,876 (326)
Arena Hukum, 2014 Thedigital technological advancement and internet technology urges the new forms of works protection against new model of piracy and copyright infringement. Technological Protection Measures (TPM) and Rights Management Information (RMI) seeks to answer
M. Zairul Alam
doaj +1 more source
Digital Rights Management and Technological Tying [PDF]
, 2008 This paper analyzes DRM-based technological tying, where the content and hardware form a system. A closed DRM system makes the legal content incompatible with a rival's hardware, whose users must then obtain illegal copies.
Kim, Jin-Hyuk - University of Cambridge
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
IIC - International Review of Intellectual Property and Competition Law, 2018 This article examines the potential and limitations of blockchain technology and blockchain-based smart contracts in relation to copyright. Copyright has long been enforced through technological means, specifically Digital Rights Management.
Michèle Finck, Valentina Moscon
semanticscholar +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Blockchain-Based Multimedia Content Protection: Review and Open Challenges
Applied Sciences, 2020 In this paper, we provide a holistic survey of multimedia content protection applications in which blockchain technology is being used. A taxonomy is developed to classify these applications with reference to the technical aspects of blockchain ...
Amna Qureshi, David Megías Jiménez
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Watermarking Protocols: A Short Guide for Beginners
Future Internet, 2023 Watermarking protocols, in conjunction with digital watermarking technologies, make it possible to trace back digital copyright infringers by identifying who has legitimately purchased digital content and then illegally shared it on the Internet ...
Franco Frattolillo
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source