Results 261 to 270 of about 10,060,996 (327)

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

Advanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li, Yike Chen, Daniel Western, Muhammad Ali, Menghan Liu, Katherine Gong, Ying Xu, Joseph Lowery, David M. Holtzman, Chloe Robins, John D. Eicher, Yen‐Ning Huang, ShiWei Liu, Tamina Park, Andrew J. Saykin, Kwangsik Nho, Mahdi Moqri, Richard C. Mohs, Amelia Farinas, Patricia Moran‐Losada, Hamilton Se‐Hwee Oh, Tony Wyss‐Coray, Carlos Cruchaga   +22 more
wiley   +1 more source

The Effectiveness, Facilitators, and Barriers of Digital Mental Health Services for First Nations People in Australia: Systematic Scoping Review.

Interact J Med Res
Zhai S, Goodman A, Smith AC, Diminic S, Zhou X.   +4 more
europepmc   +1 more source

Intelligent Stain‐Free Histology on Structural Colorimetric Nanocavities

Advanced Science, EarlyView.
Chen and Gan et al. introduce a label‐free imaging platform using inexpensive Nanocavity‐on‐Silicon (NOS) slides. These slides transform subtle tissue variations into vivid structural colors, enabling high‐contrast histological imaging under a regular optical microscope. This stain‐free approach reveals morphological details comparable to traditional H&
Qizhe Chen, Yifei Ren, Lijie Hu, Yanyan Li, Wenyue Liang, Jin Wang, Han Gao, Xinhai Wang, Jiajun Li, Qiutao He, Yingfeng Zhu, Haifeng Hu, Qiwen Zhan, Imed Gallouzi, Jasmeen Merzaban, Di Wang, Zunguo Du, Xiaodong Gu, Qiaoqiang Gan   +18 more
wiley   +1 more source

Digital inclusion and urban-rural integration: Mechanisms and regional heterogeneity in China. [PDF]

PLoS One
Qiu X, Yu M, Chen X.
europepmc   +1 more source

Multimodal Optical Imaging and Modulation with Simultaneous Electrophysiology Through Smart Dura in Non‐Human Primates

Advanced Science, EarlyView.
This study demonstrates multimodal integration in non‐human primates, combining large‐scale, high‐density electrophysiology using Smart Dura with optical techniques such as multiphoton imaging (MPI), photothrombotic lesioning, optical coherence tomography angiography (OCTA), wide‐field intrinsic signal optical imaging (ISOI), and optogenetics.
Nari Hong, Sergio Montalvo Vargo, Gaku Hatanaka, Zhaoyu Gong, Noah Stanis, Jasmine Zhou, Tiphaine Belloir, Ruikang K. Wang, Wyeth Bair, Maysamreza Chamanzar, Azadeh Yazdan‐Shahmorad   +10 more
wiley   +1 more source

The digital transformation of healthcare: a national cross-sectional study on usage, patterns, attitudes, and barriers across social groups in Israel. [PDF]

Front Public Health
Toren O, Madar G, Reicher S.
europepmc   +1 more source

Digital healthcare services in the context of age-friendly community initiatives in China: a realist evaluation. [PDF]

BMC Health Serv Res
Zhao Y, Lu G, Fang S, Cai L, He X, Liang Y.   +5 more
europepmc   +1 more source

Using real-world evidence to evaluate the long-term health and economic impact of the digital tool Grohealth W8Buddy supporting access to specialist weight management services: a protocol for a cohort observational study. [PDF]

BMJ Open
Deo PS, Grove A, Zhang M, Abrams KR, Auguste P, Barber TM, Gazeley T, Green R, Griffiths F, Hazlehurst J, Hee SW, Kaura A, Mallipedhi A, O'Toole S, Panesar A, Parsons N, Scott E, Summers C, Thind M, Thorpe M, Zalin A, Hanson P.   +21 more
europepmc   +1 more source