Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton +13 more
wiley +1 more source
Problematic mental health-related advice: exploring the role and limitations of EU's digital toolbox on the case of #TherapyTok. [PDF]
Petročnik T.
europepmc +1 more source
Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li +8 more
wiley +1 more source
Centers for Medicare & Medicaid Services to Launch Landmark ACCESS Program. [PDF]
Rebernik D.
europepmc +1 more source
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo +10 more
wiley +1 more source
Building a single market for data: Data spaces as pro-competitive infrastructure. [PDF]
Konstantopoulou ES.
europepmc +1 more source
Self‐Assembly of Organic–Inorganic Copolymers Toward Bio‐Inspired Cementitious Composites
Organic–inorganic copolymerization of calcium silicate hydrate and thioctic acid produces a self‐organized nanocomposite inspired by the disordered collagen–mineral architecture of trabecular bone. The resulting material combines a compressive strength above 300 MPa with intrinsic physical reprocessibility, retaining over 80% of its strength and energy
Zonglin Xie +8 more
wiley +1 more source
Accessibility of Digital Financial Applications for People With Visual Impairment: Scoping Review. [PDF]
Puli L +5 more
europepmc +1 more source
Vision begins not with images but with change: the retina fires only when something moves, handing the brain a stream of spikes. A neuromorphic imaging system adopts the same strategy—an event sensor that sees like the retina, a spiking network that thinks like the brain—to track and reconstruct fully randomly moving targets through tissue (phantom ...
Ning Zhang, Arto Nurmikko
wiley +1 more source
Feasibility and acceptability of a guided internet-based acceptance and commitment therapy intervention (MobACT) for adults with chronic pain in Italy: A pilot mixed-methods randomized controlled trial. [PDF]
Semonella M +16 more
europepmc +1 more source

