Results 81 to 90 of about 8,846,368 (309)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Performance analysis of RFID localization based on dual-tag range sensors
EURASIP Journal on Advances in Signal ProcessingIndoor localization based on radio technology has been a long-standing issue for the past two decades. In this paper, we study the localization problem by using dual-tag range sensors.
Feng Zheng, Thomas Kaiser
doaj +1 more source
Biomedical bulk data processing program [PDF]
, 1969 Analog-to-digital computer accepts physiological flight data as three basic analog input signals - the ECG signal, the flowmeter signal which is a respiration monitor, and the accelerometer signal which measures the normal-g-load on the ...
core +1 more source
Digital Signal Processing [PDF]
, 1976 Contains research objectives and summary of research on seven research projects.U. S. Navy Office of Naval Research (Contract N00014-75-C-0951)National Science Foundation (Grant ENG71-02319 ...
Chan, David S. K. +10 more
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Electric field measuring and display system [PDF]
, 1974 An apparatus is described for monitoring the electric fields of cloud formations within a particular area. It utilizes capacitor plates that are alternately shielded from the clouds for generating an alternating signal corresponding to the intensity of ...
Lovall, D. D., Wojtasinski, R. J.
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Interactive digital signal processor [PDF]
The Interactive Digital Signal Processor (IDSP) is examined. It consists of a set of time series analysis Operators each of which operates on an input file to produce an output file.
Behannon, K. W. +3 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Real-time adaptive filtering of dental drill noise using a digital signal processor [PDF]
, 2006 The application of noise reduction methods requires the integration of acoustics engineering and digital signal processing, which is well served by a mechatronic approach as described in this paper.
Atherton, MA +3 more
core