Results 141 to 150 of about 396,336 (296)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

Digital Skills in Perspective: A Critical Reflection on Research and Policy

open access: yesMedijske Studije, 2012
In this article we will reflect on the evolving focus of research on digital skills over the past 15 years and discuss the outcomes of this research and their implications for policy. Policy issues regarding digital skills have shifted over time.
Jos de Haan, Nathalie Sonck
doaj  

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Basic computer literacy skills expected of students by instructors at Wisconsin Indianhead Technical College [PDF]

open access: yes, 2001
Plan BThis study examined the basic computer literacy skills expected of first year students at Wisconsin Indianhead Technical College (WITC) in the Fall 2000 semester.
Pennings, Robert D.
core  

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

Self-discovery through digital portfolios: a holistic approach to developing new library and information professionals

open access: yes, 2008
Library educators face ever-increasing challenges in terms of delivering a curriculum that will adequately prepare students for the dynamic digital environment they will be working in.
Hallam, Gillian
core  

Digital Humanities and Digital Skills in the Future of Work

open access: yes
The volume covers the field of digital humanities regarding the future of work. What digital skills will be needed in the nearby future? How digitization and digitalization change the very nature of science and the workplace? The authors represent higher

core   +1 more source

Digital skills and labour opportunities for low-skilled woman

open access: yes, 2015
Con el aumento de la importancia de las tecnologías digitales en la economía, las competencias digitales son una de las nuevas demandas de la mano de obra. Esto representa nuevos retos para la igualdad de género, ya que las habilidades digitales están desigualmente distribuidas y mujeres de bajo nivel educativo son el grupo social más desfavorecido ...
Arroyo, Lídia, Valenduc, Gérard
openaire   +2 more sources

Skills for digital preservation

open access: yes, 2017
Introduction to the skills required for digital preservation for the PASIG 2017 Oxford Bootcamp Day on 11 September 2017.
Mason, Sarah, Pretlove, Lee
openaire   +1 more source

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