Results 31 to 40 of about 37,070,877 (240)
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Digital Skills and Competencies in Schools [PDF]
, 2014 This paper will compare a range of recently developed frameworks, which identify digital skills and competencies drawn from the United Kingdom (UK), from across the wider European Union, and internationally to include Australia. It will also briefly explore who and what is driving this agenda.
openaire +2 more sources
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Assessment of Digital Collaboration Skills
Proceedings of the Annual Hawaii International Conference on System SciencesThis exploratory study proposes a methodology for assessing digital collaboration skills based on the students' actual behavior. Students' comments using a digital collaboration tool during a one-month long project were manually coded. This methodology is not context specific and can be used across different domains. This assessment contrasts with self-
Huerta, Esperanza +2 more
openaire +3 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Presentation skills - workshop 2
, 2013 Handouts and instructions to prepare for delivering a 1 hour workshop on presentation skills.
Skills@Library
core
Skills At Work, 1986 to 2006 [PDF]
, 2007 This report examines the skills used by British workers and highlights a significant increase in job skills over the last two decades, with computing and 'influencing' skills in particular growing in importance over the last five years.
Gallie, Duncan +3 more
core
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
, 2011 This unit contains a PowerPoint presentation about assessing key skills, with explanatory notes, and an audio recording of the two authors talking through the presentation.
Dr Rosalind Duhs +3 more
core