Results 41 to 50 of about 2,326,458 (288)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Exploring Regional Development of Digital Humanities Research: A Case Study for Taiwan

, 2014
This study analyzed references and source papers of the Proceedings of 2009-2012 International Conference of Digital Archives and Digital Humanities (DADH), which was held annually in Taiwan.
Chen, Kuang-hua, Hsueh, Bi-Shin
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Colonization by Algorithms in the Fourth Industrial Revolution

IEEE Access, 2022
Data gathering and information processing have evolved to where it is almost unfathomable how much exists in digital form today. The generation thereof also no longer involves an explicit instruction from human to machine but can happen in real-time ...
Wynand Lambrechts, Saurabh Sinha, Sarah Mosoetsa   +2 more
doaj   +1 more source

Galaxy Cluster Environments of Radio Sources

, 2011
Using the Sloan Digital Sky Survey (SDSS) and the FIRST (Faint Images of the Radio Sky at Twenty Centimeters) catalogs, we examined the optical environments around double-lobed radio sources. Previous studies have shown that multi-component radio sources
Abazajian, Ascasibar, Bahcall, Blanc, Blanton, Blanton, Blanton, Blanton, Blanton, Blanton, Bower, Bradač, Brodwin, Budavári, Burns, Clarke, Condon, Croft, Csabai, Daddi, Dalton, Deltorn, Dickinson, D’Onghia, Elizabeth L. Blanton, Fanaroff, Gal, Garilli, Gladders, Gladders, Gladders, Gómez, Ivezić, Jee, Joshua D. Wing, Koester, Koester, Krick, Lin, Lin, Lin, Lumsden, Martini, McMahon, Menanteau, Miller, Oklopčić, Ostrander, Owen, Oyaizu, Proctor, Reiprich, Roettiger, Sarazin, Schlegel, Smith, Smolčić, Vanderlinde, Vikhlinin, Voges, Wen, York, Zirbel, Zwicky   +63 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Web services synchronization health care application

, 2011
With the advance of Web Services technologies and the emergence of Web Services into the information space, tremendous opportunities for empowering users and organizations appear in various application domains including electronic commerce, travel ...
Akaichi, Jalel, Limam, Hela
core   +1 more source

Digital curation skills in the performing arts: an investigation of practitioner awareness and knowledge of digital object management and preservation [PDF]

, 2014
This study examines the digital curation awareness and practice of a sample of practitioners from the UK performing arts community. Twelve performance arts practitioners from across the United Kingdom were interviewed to establish understanding of ...
Molloy, Laura
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

DER STURM

RIDE, 2023
This paper reviews the digital edition Der Sturm – Digitale Quellenedition zur Geschichte der internationalen Avantgarde, which aims to bring together all existing digital sources on the STURM company, to make them accessible and to link them with each ...
Lisa Dieckmann
doaj   +1 more source