Results 51 to 60 of about 1,525,412 (268)

Digital Stress and Performance: The Role of Supervisor Support and Technology Self-Efficacy as Moderators

open access: yesJurnal Psikologi
Technology revolution has brought consistent changes in the modern workplace. There are potential dangers from information overload and stress from the use of ICT in the workplace.
Janu Nugraha Ramadhan
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Digital Equipment Effective Stress Measure [PDF]

open access: yes, 2001
In this thesis, we presented the design of measuring devices, which may be used to measure the effective voltage value of an electrical signal.operation of this measuring instrument used for measuring the effective price of the wavesthat shaped not ...
Jalinas, SKom, MM Jalinas, SKom, MM   +1 more
core  

The post-yield fracture of a ductile polymer film: Notch quality, essential work of fracture, crack tip opening displacement, and J-integral [PDF]

open access: yes, 2017
Double edge notched tension (DENT) specimens of a polyethylene terephthalate (PET) film were tested in an universal testing machine, measuring the displacements and the ligament lengths with a digital image correlation (DIC) system.
Arencón Osuna, David   +3 more
core   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Exploring preservice teachers’ digital skills, stress, and coping strategies during online lessons amid covid-19 pandemic in Ghana

open access: yesCogent Education, 2022
There are concerns about the association between the level of students’ digital skills and the amount of stress they experience. However, evidence from both cross-sectional and longitudinal studies is limited.
Christopher Yaw Kwaah   +4 more
doaj   +1 more source

Measuring digital stress in the workplace context

open access: yesInformatik Spektrum, 2023
AbstractDigital stress is a form of stress caused by the use and ubiquity of digital technologies. More and more scientists and practitioners are interested in the phenomenon of digital stress, its causes (e.g., constant smartphone accessibility, unreliable and unstable systems, information overload), and its consequences (e.g., negative health effects,
René Riedl   +2 more
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Validation of the hypothesis on the protective role of functional beverages in mitigating the adverse health effects of digital technologies

open access: yesFrontiers in Nutrition
The widespread adoption of digital technologies (DT) and artificial intelligence (AI) has led to the emergence of digital stress (DS), characterized by anxiety, cognitive overload, visual fatigue, and emotional exhaustion. This study aims to validate the
Mukhtar Tultabayev   +3 more
doaj   +1 more source

Digital music interventions for stress with bio-sensing: a survey

open access: yesFrontiers in Computer Science, 2023
Music therapy is used to treat stress and anxiety in patients for a broad range of reasons such as cancer treatment, substance abuse, addressing trauma, and just daily stress in life.
Arron Ferguson   +2 more
doaj   +1 more source

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