Results 51 to 60 of about 1,626,190 (282)

A Study of Stress Analysis for a Residual Stress Model by Digital Photoelasticity [PDF]

open access: yesApplied Mechanics and Materials, 2008
The stress analysis for a model with initial stresses, which we term a residual stress model, is performed by digital photoelasticity. The stresses applied on the residual stress model are obtained by analyzing both the initial stresses and the resultant stresses.
openaire   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Concrete Static Stress Estimation Using Computer Vision-Based Digital Image Processing [PDF]

open access: yes, 2018
Department of Urban and Environmental Engineering (Urban Infrastructure Engineering)As increasing interests about structural safety due to occasionally occurring collapse of structures and social infrastructures, efforts to identify and monitor the ...
Kim, Eun Jin
core  

Computer program calculates steady-state temperature distribution within plane or axisymmetric solids [PDF]

open access: yes, 1967
Digital computer program, using the finite element analysis technique, determines the steady-state temperature within plan or axisymmetric solids composed of many different materials of various geometry.
Wilson, E. L.
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Uncovering the Impact of Digitalization on the Performance of Insurance Distribution

open access: yesRisks
This study explores the impact of digitalization on the performance of insurance intermediaries, who still play a key role in the revenue generation of insurance companies.
Thomas Köhne, Marija Köhne
doaj   +1 more source

Smartphone-Tracked Digital Markers of Momentary Subjective Stress in College Students: Idiographic Machine Learning Analysis

open access: yesJMIR mHealth and uHealth, 2023
BackgroundStress is an important predictor of mental health problems such as burnout and depression. Acute stress is considered adaptive, whereas chronic stress is viewed as detrimental to well-being. To aid in the early detection
George Aalbers   +3 more
doaj   +1 more source

A stress free model for residual stress assessment using thermoelastic stress analysis [PDF]

open access: yes, 2014
Thermoelastic Stress Analysis (TSA) has been proposed as a method of obtaining residual stresses. The results of a preliminary study demonstrated that when Al-2024 plate containing holes that were plastically deformed by cold expansion process to 2% and ...
Achintha, Mithila   +3 more
core   +1 more source

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