Results 51 to 60 of about 27,515,164 (308)

Analysis of the Challenges of Artificial Intelligence of Things (AIoT) for the Smart Supply Chain (Case Study: FMCG Industries)

Sensors, 2022
In today’s competitive world, supply chain management is one of the fundamental issues facing businesses that affects all an organization’s activities to produce products and provide services needed by customers.
Hamed Nozari, Agnieszka Szmelter-Jarosz, Javid Ghahremani-Nahr   +2 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

How Should I Teach from This Month Onward? A State-Space Model That Helps Drive Whole Classes to Achieve End-of-Year National Standardized Test Learning Targets

Systems, 2022
Every month, teachers face the dilemma of what exercises their students should practice, and what their consequences are regarding long-term learning. Since teachers prefer to pose their own exercises, this generates a large number of questions, each one
Obed Ulloa, Roberto Araya
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

DIGITAL DATA-DRIVEN APPROACHES TO MONITOR AND FOSTER WELL-BEING AMONG EXCHANGE STUDENTS DURING DISRUPTIVE EVENTS

Автоматизация технологических и бизнес-процессов
In today’s rapidly changing world, marked by collective crises, the digitalization of academic mobility management processes plays a crucial role in enhancing the effectiveness of educational programs.
Anastasiia Volkova, Nadiia Dets, Olshevska Olga, Yulia Tsarynna, Liudmyla Fihurska   +4 more
doaj   +1 more source

Improving Diuretic Response in Heart Failure by Implementing a Patient-Tailored Variability and Chronotherapy-Guided Algorithm

Frontiers in Cardiovascular Medicine, 2021
Heart failure is a major public health problem, which is associated with significant mortality, morbidity, and healthcare expenditures. A substantial amount of the morbidity is attributed to volume overload, for which loop diuretics are a mandatory ...
Ariel Kenig, Yotam Kolben, Rabea Asleh, Offer Amir, Offer Amir, Yaron Ilan   +5 more
doaj   +1 more source

Digitized Educational System

, 2021
Today’s society, economy, and community are involved in terms of information technology usage. Thai university is a national university that has been highly supported by the Thai government. The term “autonomous university” refers to being independently organized under “bureaucratic frameworks.” In other words, being an autonomous university lets the ...
Suppanunta, Romprasert,, Jirayut, Monjagapate,   +1 more
openaire   +3 more sources

Digital Transformation and Flexible Performance Management: A Systematic Literature Review of the Evolution of Performance Measurement Systems

Global Journal of Flexible Systems Management
In the era of digital transformation, businesses must innovate and adapt to sustain a competitive edge. This dynamic environment compels a reevaluation of traditional management practices, highlighting the need for highly flexible systems.
M. Cosa, Riccardo Torelli
semanticscholar   +1 more source

Application of Digital Twin in Smart Battery Management Systems

, 2021
Lithium-ion batteries have always been a focus of research on new energy vehicles, however, their internal reactions are complex, and problems such as battery aging and safety have not been fully understood.
Wenwen Wang, J. Wang, Jinpeng Tian, Jiahuan Lu, R. Xiong   +4 more
semanticscholar   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source