Results 41 to 50 of about 2,370,521 (309)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Languages, 2021 This paper presents an analysis of poems, digital art, and accompanying analytical essays authored by four college students taking an advanced Spanish as heritage language.
María Luisa Parra
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Digitalization in Teaching Economic Disciplines: Past, Current and Future Perspectives
Business Systems Research, 2022 This special issue of Business Systems Research (SI of the BSR) highlights the past, current and future perspectives of digitalization in teaching economic disciplines. The emphasis has been put on digital competencies, the quality of e-learning, e-exams,
Dečman Nikolina, Rep Ana
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Interoperability of Digital Tools for the Monitoring and Control of Construction Projects
Applied Sciences, 2021 Monitoring the progress on a construction site during the construction phase is crucial. An inadequate understanding of the project status can lead to mistakes and inappropriate actions, causing delays and increased costs.
Luz Duarte-Vidal +3 more
doaj +1 more source
Harnessing the creativity of digital multimedia tools in distance learning [PDF]
, 2012 Over the past few decades, advances in information and communication technologies, and particularly the digitisation of information, have brought about radical changes in the way media can be produced, distributed and shared. The exchange of information,
Kouadri Mostéfaoui, Soraya +1 more
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
International Journal of Engineering and Advanced Technology, 2019 In this paper we will we reviewing the basic fundamentals of digital forensics and all go through the various types of forensics investigation teams available to us. We will also discuss about the different types of digital crimes that take place and the various tools present in order to counteract the crimes that are being committed.
Vedanta Kapoor +2 more
openaire +1 more source
Flight test validation of a design procedure for digital autopilots [PDF]
, 1983 Commercially available general aviation autopilots are currently in transition from an analogue circuit system to a computer implemented digital flight control system.
Bryant, W. H.
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source