Results 61 to 70 of about 2,370,521 (309)

My digital photos: where and when? [PDF]

, 2005
In recent years digital cameras have seen an enormous rise in popularity, leading to a huge increase in the quantity of digital photos being taken. This brings with it the challenge of organising these large collections.
Gurrin, Cathal, Jones, Gareth J.F., Lee, Hyowon, Murphy, Noel, O'Hare, Neil, Smeaton, Alan F.   +5 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Digital tools in urban forestry

npj Urban Sustainability
Digital tools are used widely to plan and manage urban forests for sustainability. We conducted a scoping review to investigate how researchers use and envision integrating digital tools into urban forestry.
Matthew Fry, Rylee Babino, Ashley R. Coles, Kaylee P. Alexander, Ben Williamson, Alexandra G. Ponette-González   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The Correlation of Digital Competence and Crisis Management: Evidence from the Polish Public Administration

Institutiones Administrationis
In the age of digitalization, when almost all aspects of social activity are effected and novel threats to a rapidly changing environment are being posed, the ability of public servants to use digital tools competently is crucial for an effective crisis ...
Krzysztof Kaczmarek, Mirosław Karpiuk, Jarosław Kostrubiec   +2 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Towards Generative Governance: Co‐Creation With Emerging Technologies to Address Climate Challenges in Cities

Urban Planning
This thematic issue explores how co‐creation processes, facilitated by emerging technologies, can help cities in addressing complex climate adaptation challenges.
Cesar Casiano Flores, A. Paula Rodriguez Müller, Evrim Tan   +2 more
doaj   +1 more source

LODE: Linking Digital Humanities Content to the Web of Data

, 2014
Numerous digital humanities projects maintain their data collections in the form of text, images, and metadata. While data may be stored in many formats, from plain text to XML to relational databases, the use of the resource description framework (RDF ...
Allen, Colin, Huber, Jakob, Murdock, Jaimie, Niepert, Mathias, Noessner, Jan, Sztyler, Timo   +5 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Workflow Tools for Digital Curation

Code4Lib Journal, 2013
Maintaining usable and sustainable digital collections requires a complex set of actions that address the many challenges at various stages of the digital object lifecycle.
Andrew James Weidner, Daniel Gelaw Alemneh   +1 more
doaj