Results 41 to 50 of about 1,376,234 (260)

Impact of Japan's 2024 Physician Work‐Style Reform on Pediatric Hematology–Oncology: Educational Implications in a 2‐Year Survey

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Japan's 2024 physician work‐style reform introduced legally binding limits on physicians’ working hours, but its impact on education and workforce sustainability in pediatric hematology–oncology (PHO) remains unclear. Procedure We conducted a repeated cross‐sectional study with structured quantitative items and free‐text responses ...
Kiyohiko Kaizu   +7 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Digital Connectivity at Work: Balancing Benefits and Risks for Engagement, Technostress, and Performance

open access: yesAdministrative Sciences
Background: The COVID-19 pandemic has accelerated the adoption of smart working and digital connectivity, transforming workplace interactions.
Giorgia Bondanini   +3 more
doaj   +1 more source

A Scoping Review of Research Exploring Working Life Practices of People with Disabilities During the COVID-19 Pandemic

open access: yesScandinavian Journal of Disability Research, 2023
There have been numerous research studies stating the fact that the pandemic affected people with disabilities’ working lives. Less research has been conducted on how people with disabilities coped with and learned from these challenges.
Magnus Eriksson   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Gig economy, rating, labour relationship

open access: yesLabour & Law Issues, 2017
In the era of gig economy, the job performance is now influenced by the customer rating system. A new London’s Employment Tribunal judgment approaches the Uber London issue focusing also on customer feedback.
Gemma Pacella
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

La tutela giuridica dell’attività creativa dei nuovi lavoratori del web

open access: yesLabour & Law Issues, 2015
This article deals with the creative activity of web workers and explores feasible forms of legal protection.Digital works, as long as characterized by a minimal creative content, are protected by copyright law as creative intellectual work.
Giusella Finocchiaro
doaj   +1 more source

Teachers’ work with digital technologies

open access: yes, 2021
Policies relating to the use of digital technologies in school usually address issues including “Appropriate Use”, “E-Safety”, network security, and data protection. However, digital technologies are now an integral part of how teachers are expected to engage with school-related work.
Selwyn, Neil, Heffernan, Amanda
openaire   +3 more sources

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