Results 151 to 160 of about 4,133,519 (389)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Parametric estimation analysis of compressive stress effects on piezoelectric properties of PZT ceramic

open access: yesJournal of Asian Ceramic Societies
In this study, the frequency and capacitance of piezoelectric materials due to compressive stress were analyzed, and the overall material properties (compliance matrix, piezoelectric charge constant and dielectric constant) of piezoelectric ceramics were
Jong-Ho Kim   +4 more
doaj   +1 more source

What Europe Knows and Thinks About Algorithms Results of a Representative Survey. Bertelsmann Stiftung eupinions February 2019 [PDF]

open access: yes, 2019
We live in an algorithmic world. Day by day, each of us is affected by decisions that algorithms make for and about us – generally without us being aware of or consciously perceiving this.
Grzymek, Viktoria, Puntschuh, Michael
core  

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

open access: yesFEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili   +2 more
wiley   +1 more source

A Deduplication and Extraction Algorithm for Frequent Itemsets of Overlapping Data Between Power Categories Based on Variable Time Windows

open access: yesInternational Journal of Computational Intelligence Systems
In the process of data extraction, the rigid partitioning mechanism of fixed time windows leads to spatiotemporal heterogeneity mismatches in data distribution, resulting in semantic confusion and redundancy accumulation in mining results. To address the
Jie Zhang   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

How can data analytics and employee upskilling foster digital maturity and sustainable practices in SMES? [PDF]

open access: yesProblems and Perspectives in Management
The accelerating pace of digital and environmental transformation presents both opportunities and challenges for small- and medium-sized enterprises (SMEs) across the European Union.
Levente Peter Balint   +3 more
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Route Optimization for UVC Disinfection Robot Using Bio-Inspired Metaheuristic Techniques

open access: yesBiomimetics
The COVID-19 pandemic highlighted the urgent need for effective surface disinfection solutions, which has led to the use of mobile robots equipped with ultraviolet (UVC) lamps as a promising technology.
Mario Peñacoba   +3 more
doaj   +1 more source

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