Results 241 to 250 of about 10,909 (272)
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Digitoxin Poisoning: Prevention by Spironolactone
Science, 1969Spironolactone (Aldactone ®) protects the rat against the production of myocardial necroses and other manifestations of digitoxin poisoning.
Laurent Savoie, M. Krajny, Hans Selye
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Digitoxin Antagonism by Visnadin
Journal of Pharmaceutical Sciences, 1962Visnadin, a lactone derived from bishop's weed, has been found to have marked antidotal properties in animals poisoned with digitoxin. It increases survival on acute and chronic administration of the glycoside, prevents the appearance of bradycardia, and reverses cardiac arrhythmias.
D.D. Varonos +2 more
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Noninteraction of Digitoxin and Quinidine
New England Journal of Medicine, 1980A LARGE and clinically important interaction between digoxin and quinidine is now well documented.1 2 3 4 5 The cardiac glycoside digitoxin is extensively used in clinical practice, but its interaction with quinidine has not been definitively evaluated.6 , 7 In this study, which assessed the pharmacokinetic interaction of digitoxin with quinidine, we ...
David J. Greenblatt +3 more
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Disposition of digitoxin in renal failure
Clinical Pharmacology & Therapeutics, 1976The disposition of digitoxin was studied for a period of 8 days in 6 uremic patients given a single oral dose of 1 mg 3 H‐digitoxin. in plasma, the time‐course of radioactivity indicated a diminished absorption velocity of tritium compared to that of control subjects already reported20 and, after reaching of a pseudostate‐equilibrium at 24 hr, an ...
Baethke R +5 more
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Accidental Digitoxin Poisoning
Archives of Pediatrics & Adolescent Medicine, 1976A healthy 141/2-month-old child ingested 1.5 mg of digitoxin by accident. Digitoxin was wrongly identified as digoxin, the initial electrocardiogram was misinterpreted, and the vomiting was underestimated as an important symptom of toxicity. Symptoms persisted and the patient was hospitalized.
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An Improved Method of Digitoxin Therapy
Annals of Internal Medicine, 1970Abstract An improved method of digitoxin therapy is presented for adult euthyroid patients of average weight with normal hepatic function, electrolyte balance, and gastrointestinal absorption whose...
R. Sridhar +5 more
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Journal of the American Pharmaceutical Association (Scientific ed.), 1953
P, DEMOEN, P, JANSSEN
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P, DEMOEN, P, JANSSEN
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Annals of Internal Medicine, 1970
Excerpt To the editor: In their article entitled "An Improved Method of Digitoxin Therapy" (Ann Intern Med72: 453-464, 1970), Jelliffe and co-workers stated under Dosage Forms of Digitoxin (p.
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Excerpt To the editor: In their article entitled "An Improved Method of Digitoxin Therapy" (Ann Intern Med72: 453-464, 1970), Jelliffe and co-workers stated under Dosage Forms of Digitoxin (p.
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1981
Digitoxin is the main cardioactive glycoside in Digitalis purpurea and was purified by Nativelle (1864). Although it was the first cardiac glycoside introduced into clinical medicine, our knowledge of its pharmacokinetics and metabolism originates from research done during the last decades.
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Digitoxin is the main cardioactive glycoside in Digitalis purpurea and was purified by Nativelle (1864). Although it was the first cardiac glycoside introduced into clinical medicine, our knowledge of its pharmacokinetics and metabolism originates from research done during the last decades.
openaire +2 more sources