Results 241 to 250 of about 10,900 (273)

Digitoxin bei hepatorenaler Insuffizienz

DMW - Deutsche Medizinische Wochenschrift, 2008
Serum digitoxin levels were measured during maintenance treatment with digitoxin, 0.1 mg daily i.v., in 12 patients under intensive postoperative care who had hepatorenal failure resulting from multiple organ failure. Thirteen patients in intensive care with comparable basic diseases served as controls; they had developed predominantly renal failure ...
Ch. Maier, K.-D. Kolenda
openaire   +3 more sources

Simultaneous quantification of digoxin, digitoxin, and their metabolites in serum using high performance liquid chromatography-tandem mass spectrometry.

Drug Testing and Analysis, 2015
The study describes an LC-MS/MS method for simultaneous quantification of the cardiac glycosidic drugs digoxin and digitoxin and several of their metabolites.
Caroline Bylda, R. Thiele, U. Kobold, D. Volmer   +3 more
semanticscholar   +1 more source

Excretion Equations and Interpretation for Digitoxin [PDF]

Nature, 1957
DR. J. SWINTOSKY has made a valuable addition to the literature of urinary excretion equations by enabling a specific velocity constant, k, to be derived from the rate of urinary excretion. The meaning of k is not discussed and superficially it appears to depend only on excretion.
J, HOUGH, J V, SWINTOSKY
openaire   +2 more sources

Gold-catalyzed diversified synthesis of 3-aminosugar analogues of digitoxin and digoxin

, 2017
A diversified synthesis of 3-aminosugar analogues of digitoxin and digoxin with potent anticancer activities was explored. The synthesis was based on a highly efficient gold-catalyzed glycosylation reaction with alkynylbenzoate 3-aminoglycosides as ...
Jing Zeng, Guangfei Sun, Ruobin Wang, Shuxin Zhang, S. Teng, Zhi-Sheng Liao, Lingkui Meng, Qian Wan   +7 more
semanticscholar   +1 more source

Digitoxin Poisoning: Prevention by Spironolactone

Science, 1969
Spironolactone (Aldactone ®) protects the rat against the production of myocardial necroses and other manifestations of digitoxin poisoning.
Laurent Savoie, M. Krajny, Hans Selye
openaire   +3 more sources

Digitoxin Antagonism by Visnadin

Journal of Pharmaceutical Sciences, 1962
Visnadin, a lactone derived from bishop's weed, has been found to have marked antidotal properties in animals poisoned with digitoxin. It increases survival on acute and chronic administration of the glycoside, prevents the appearance of bradycardia, and reverses cardiac arrhythmias.
D.D. Varonos, G.C. Nikitopoulou, P.C. Voukydes   +2 more
openaire   +3 more sources

Synthesis of cardiac glycoside analogs by catalyst-controlled, regioselective glycosylation of digitoxin.

Organic Letters, 2013
The cardiac glycoside natural product digitoxin was selectively glycosylated at one of its five hydroxyl groups using a borinic acid derived catalyst.
Thomas M. Beale, M. Taylor
semanticscholar   +1 more source

Noninteraction of Digitoxin and Quinidine

New England Journal of Medicine, 1980
A LARGE and clinically important interaction between digoxin and quinidine is now well documented.1 2 3 4 5 The cardiac glycoside digitoxin is extensively used in clinical practice, but its interaction with quinidine has not been definitively evaluated.6 , 7 In this study, which assessed the pharmacokinetic interaction of digitoxin with quinidine, we ...
David J. Greenblatt, Hermann R. Ochs, Hans J. Dengler, Joachim Pabst   +3 more
openaire   +3 more sources

Catalytic stereoselective synthesis of β-digitoxosides: direct synthesis of digitoxin and C1'-epi-digitoxin.

Journal of Organic Chemistry, 2013
A mild and atom-economic rhenium(V)-catalyzed stereoselective synthesis of β-D-digitoxosides from 6-deoxy-D-allals has been described. This β-selective glycosylation was achieved probably because of the formation of corresponding α-digitoxosides ...
K. Baryal, Surya B. Adhikari, Jianglong Zhu   +2 more
semanticscholar   +1 more source

Disposition of digitoxin in renal failure

Clinical Pharmacology & Therapeutics, 1976
The disposition of digitoxin was studied for a period of 8 days in 6 uremic patients given a single oral dose of 1 mg 3 H‐digitoxin. in plasma, the time‐course of radioactivity indicated a diminished absorption velocity of tritium compared to that of control subjects already reported20 and, after reaching of a pseudostate‐equilibrium at 24 hr, an ...
Baethke R, H. F. Vöhringer, J. Kuhlmann, Spurny P, N. Rietbrock, Hampl H   +5 more
openaire   +3 more sources