Results 161 to 170 of about 567,985 (207)

Digoxin Toxicity in Patients with High Serum Digoxin Concentrations

American Journal of the Medical Sciences, 1987
A retrospective study of the clinical course and outcome of patients with serum digoxin concentrations (SDCs) greater than 3 ng/mL was conducted to determine the probability of a patient without initial signs or symptoms of digoxin toxicity subsequently developing signs or symptoms.
M J Goldberg
exaly   +3 more sources

Physiologically based pharmacokinetic modelling of acute digoxin toxicity and the effect of digoxin-specific antibody fragments

Clinical Toxicology, 2019
Context: Recommended doses of digoxin-specific antibody fragments (digoxin-Fab) for treatment of acute digoxin poisoning are pharmacokinetically unsubstantiated and theoretically excessive.
Lucy Bracken, Nicholas Buckley, Betty Chan   +2 more
exaly   +2 more sources

Roxithromycin‐induced digoxin toxicity

Medical Journal of Australia, 1996
A 76-year-old women presented with digoxin toxicity four days after starting a course of roxithromycin. In 10%-15% of the population, digoxin is degraded extensively by bacteria in the gastrointestinal tract, and antibiotic-induced changes in the bacterial flora may lead to digoxin toxicity.
C E, Corallo, I R, Rogers
openaire   +2 more sources

Economic Impact of Digoxin Toxicity

PharmacoEconomics, 1997
The costs of digoxin toxicity to the US healthcare system have not been previously reported. Therefore, the 1994 database of US University Health-System Consortium (UHC) was searched for cases of digoxin toxicity using the International Classification of Diseases (9th edition) [ICD-9] codes.
A J, Gandhi, P H, Vlasses, D J, Morton, J L, Bauman   +3 more
openaire   +2 more sources

Expert Consensus on the Diagnosis and Management of Digoxin Toxicity

American Journal of Medicine
While there has been a decline in the use of digoxin in patients with heart failure and atrial fibrillation, acute and chronic digoxin toxicity remains a significant clinical problem.
Michael W Rich, Paul Hauptman
exaly   +2 more sources

Hemofiltration for Digoxin Toxicity

Archives of Internal Medicine, 1986
To the Editor. —Regarding the article by Lai et al on "Hemofiltration in Digoxin Overdose" that appeared in the June issue of theArchives, 1 I should like to point out that only about 15% to 20% (0.15 to 0.25) of digoxin is protein bound, contrary to the figure quoted by the authors.
openaire   +2 more sources

Alprazolam-related digoxin toxicity

American Journal of Psychiatry, 1984
An elderly woman developed a high serum digoxin concentration resulting in toxicity when alprazolam was added to her digoxin therapy. The reduced renal clearance of digoxin is postulated as the mechanism for this interaction.
G, Tollefson, T, Lesar, D, Grothe, M, Garvey   +3 more
openaire   +2 more sources

Omeprazole-associated Digoxin Toxicity

Southern Medical Journal, 2007
Omeprazole is a commonly prescribed inhibitor of the gastric proton pump and has numerous indications in the treatment of gastrointestinal diseases. It is primarily metabolized through the CYP2C19 enzyme, a member of the P450 mixed-function oxidase group, although a minor pathway of metabolism is through CYP3A4, another P450 enzyme.
Cristin A, Kiley, Douglas J, Cragin, Bernard J, Roth   +2 more
openaire   +2 more sources

Digoxin Toxicity

AJN, American Journal of Nursing, 1993
inda Hendricks, the nurse assigned to Mr. Bradley, a 75-year-old man with congestive heart failure and chronic renal insufficiency, was concerned. Mr. Bradley's CHF had seemed to be responding to digoxin and furosemide (Lasix). But now, on his fourth hospital day, this usually talkative and energetic man had become lethargic and withdrawn. He'd refused
openaire   +2 more sources

Digoxin specific antibody fragments (Digibind) in digoxin toxicity

BMJ, 2009
Digoxin levels may be falsely raised after administration of digoxin specific antibody ...
Dorothy, Ip, Hafiz, Syed, Maurice, Cohen
openaire   +2 more sources