Results 151 to 160 of about 56,351 (299)
Nano Select, EarlyView.Improving selectivity within therapeutic design is critical to ensure targeted delivery to brain tumors. Targeting the cellular membrane composition distinctive of the blood–brain barrier and brain cancer cells is explored in this review. Nanomedicine can be utilized for precise tumor recognition, and detailed mechanistic interactions of therapeutics ...
Mahnoor Kadri +2 more
wiley +1 more source
ChemistryOpen, EarlyView.X‐ray crystallographic analysis of super‐folder green fluorescent protein (sfGFP), a common reporter protein, displaying p‐(phenylazo)‐L‐phenylalanine (Pap) at amino acid position 39 on its surface in complex with α‐cyclodextrin (α‐CD) reveals an unexpected conformation of the photoswitchable side chain and illustrates its light‐dependent ...
Andreas Eichinger +4 more
wiley +1 more source
Improving the performance of the PLB index for ligand-binding site prediction using dihedral angles and the solvent-accessible surface area. [PDF]
Sci Rep, 2016 Cao C, Xu S.
europepmc +1 more source
Convex Polytopes, Dihedral Angles, Mean Curvature and Scalar Curvature
Discrete & Computational GeometryWe approximate boundaries of convex polytopes by smooth hypersurfaces $Y=Y_\varepsilon$ with {\it positive mean curvatures} and, by using basic geometric relations between the scalar curvatures of Riemannin manifolds and the mean curvatures of their boundaries, establish {\it lower bound on the dihedral angles} of these polytopes.
openaire +2 more sources
Polymer International, EarlyView.A new organic molecular cathode interlayer is presented built upon the perylene butyl tetraester scaffold. The new molecule incorporates N‐annulation and a functional amine group to control optical, electrochemical and physical properties and delivers excellent solar cell performance. Abstract We report a new amino‐bay‐substituted, N‐annulated perylene
Kathryn M Wolfe +7 more
wiley +1 more source
Structural Modeling and Dynamics of the Full‐Length Homer1 Multimer
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Homer proteins are modular scaffold molecules that constitute an integral part of the protein network within the postsynaptic density. Full‐length Homer1 forms a large homotetramer via a long coiled coil region, and can interact with proline‐rich target sequences with its globular EVH1 domain.
Zsófia E. Kálmán +9 more
wiley +1 more source
Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley +1 more source
Intrinsic mechanical properties of two-dimensional covalent organic frameworks. [PDF]
Chem SciXiong L +6 more
europepmc +1 more source
Boron Difluoride Chelated Aminoanthraquinone Photosensitizer for Type I Photodynamic Therapy
Rare Metals, EarlyView.ABSTRACT Type I photosensitizers capable of generating cytotoxic reactive oxygen species (ROS), with reduced oxygen dependence under photoirradiation, are regarded as a promising phototherapeutic approach for hypoxic solid tumors. Herein, based on the electron donor of 9‐phenyl‐carbazole (Cz) and the electron acceptor of anthraquinone (AQ ...
Tian Zhang +8 more
wiley +1 more source