Results 201 to 210 of about 105,161 (275)

Molecular dynamics simulations and fluorescence spectroscopy suggest reduced tryptophan‐to‐heme energy transfer facilitates lignin degradation in ClassII peroxidases

open access: yesThe FEBS Journal, EarlyView.
In lignin peroxidase and versatile peroxidase, low FRET from buried Trp to heme promotes long‐range electron transfer (LRET) from substrate to heme. This efficient electron flow is facilitated by reduced FRET competition. This mechanism likely evolved to enable the effective degradation of bulky, high‐redox‐potential lignin that cannot reach the enzyme'
Yi Ren   +6 more
wiley   +1 more source

Emergence of Continents Stabilized the Bioavailability of Boron

open access: yesTerra Nova, EarlyView.
ABSTRACT Boron is an essential element for the development of life on Earth; borates stabilize ribose in prebiotic reactions and facilitate metabolism in higher plants. There is, however, a relatively narrow surface boron concentration range over which borates stabilize and serve as a micronutrient rather than a toxin.
Brendan V. Dyck, Jon Wade
wiley   +1 more source

Effects of Donor Rigidity on Coumarin Delayed Emission: New Tricks from Old Materials. [PDF]

open access: yesJ Phys Chem Lett
Paredis S   +10 more
europepmc   +1 more source

Stimuli‐Responsive Poly(Disulfide)s: A Versatile Platform for Intelligent Drug Delivery Systems

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Ring‐opening polymerization based on dynamic disulfide bond exchange is an important method for synthesizing poly(disulfide)s. These polymers possess stimulus‐responsive mechanisms and show broad prospects in intelligent drug delivery. This review systematically discusses the ring‐opening polymerization strategy and research progress of drug delivery ...
Yuechen He   +7 more
wiley   +1 more source

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu   +9 more
wiley   +1 more source

Counting particles in cryo-electron microscopy may result in incorrect population estimates. [PDF]

open access: yesCommun Biol
Evans L   +5 more
europepmc   +1 more source

Synthesis, X‐Ray Analysis, Anticancer Activity, Computational, and in Silico Studies of New Thiophene Pyrazole Conjugates

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
Two new thiophene–pyrazole derivatives, 8a and 8b, were synthesized from thiophene 3 precursor and fully characterized. The structure of 8a was confirmed by single‐crystal X‐ray diffraction, which revealed a nonplanar conformation stabilized by NH···O hydrogen bonding and weak intermolecular contacts.
Abdullatif Bin Muhsinah   +3 more
wiley   +1 more source

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