Results 101 to 110 of about 9,205 (218)

Reactive Oxygen Species: From Tumorigenesis to Therapeutic Strategies in Cancer

Cancer Medicine, Volume 14, Issue 10, May 2025.
ABSTRACT Background Reactive oxygen species (ROS), a class of highly reactive molecules, are closely linked to the pathogenesis of various cancers. While ROS primarily originate from normal cellular processes, external stimuli can also contribute to their production. Cancer cells typically exhibit elevated ROS levels due to disrupted redox homeostasis,
Iqra Attique, Zahra Haider, Maha Khan, Samina Hassan, Mohamed Mohamed Soliman, Wisam Nabeel Ibrahim, Sumaira Anjum   +6 more
wiley   +1 more source

Accessing the genomic information of unculturable oceanic picoeukaryotes by combining multiple single cells [PDF]

, 2017
Mangot, Jean-François et al.-- 12 pages, 7 figures, 2 tables, supplementary information https://dx.doi.org/10.1038/srep41498Pico-sized eukaryotes play key roles in the functioning of marine ecosystems, but we still have a limited knowledge on their ...
Latorre, Fran, Logares, Ramiro, Mangot, Jean-François, Massana, Ramon, Sánchez, Pablo   +4 more
core   +1 more source

Extracellular vesicle proteomics uncovers energy metabolism, complement system, and endoplasmic reticulum stress response dysregulation postexercise in males with myalgic encephalomyelitis/chronic fatigue syndrome

Clinical and Translational Medicine, Volume 15, Issue 5, May 2025.
EVs were isolated from plasma of ME/CFS patients and healthy controls at baseline, and 15 min and 24 h postexercise. Untargeted proteomics revealed dysregulation in energy metabolism, the complement system, and the endoplasmic reticulum stress response. Changes in EV protein levels postexercise are associated with post‐exertional malaise.
Katherine A. Glass, Ludovic Giloteaux, Sheng Zhang, Maureen R. Hanson   +3 more
wiley   +1 more source

Asperuloside stimulates metabolic function in rats across several organs under high-fat diet conditions, acting like the major ingredient of Eucommia leaves with anti-obesity activity

Journal of Nutritional Science, 2012
Eucommia leaves (Eucommia ulmoides Oliver) contain chlorogenic acid (a caffeic acid derivative) and geniposidic acid and asperuloside (ASP), iridoid glucosides used in beverages. We used a metabolic syndrome rat model, produced by feeding a 35 % high-fat
Takahiko Fujikawa, Tetsuya Hirata, Shingo Hosoo, Kenji Nakajima, Atsunori Wada, Yutaka Yurugi, Hideaki Soya, Takashi Matsui, Akihiko Yamaguchi, Masato Ogata, Sansei Nishibe   +10 more
doaj   +1 more source

RNA‐seq analysis of mitochondria‐related genes regulated by AMPK in the human trophoblast cell line BeWo

Animal Models and Experimental Medicine, Volume 8, Issue 4, Page 649-661, April 2025.
Using RNA‐seq and other bioinformatics analyses, three clusters of mitochondria related genes, including aldo‐keto reductase family 1 members B10 and B15 (AKR1B10, AKR1B15), alanyl‐tRNA synthetase 1 (AARS1), mitochondrial ribosomal protein S6 (MRPS6), mitochondrial calcium uniporter dominant negative subunit beta (MCUB) and dihydrolipoamide branched ...
Bin Wu, Albert Gao, Bin He, Yun Chen, Xiangfeng Kong, Fayuan Wen, Haijun Gao   +6 more
wiley   +1 more source

Sulforaphane, a cancer chemopreventive agent, induces pathways associated with membrane biosynthesis in response to tissue damage by aflatoxin B1 [PDF]

, 2014
Aflatoxin B[subscript 1] (AFB[subscript 1]) is one of the major risk factors for liver cancer globally. A recent study showed that sulforaphane (SF), a potent inducer of phase II enzymes that occurs naturally in widely consumed vegetables, effectively ...
Croy, Robert G, Essigmann, John M, Fiala, Jeanette LouiseAllen, Groopman, John D., Navasumrit, Panida, Ruchirawat, Mathuros, Techapiesancharoenkij, Nirachara, Wogan, Gerald N   +7 more
core   +1 more source

Mitochondrial Oxygen Consumption by the Foreskin and its Fibroblast-rich Culture

Sultan Qaboos University Medical Journal, 2013
Objectives: This study investigated the feasibility of using a phosphorescence oxygen analyser to measure cellular respiration (mitochondrial O2 consumption) in foreskin samples and their fibroblast-rich cultures.Methods: Foreskin specimens from normal ...
Fatma Al-Jasmi, Thachillath Pramathan, Adnan Swid, Bahjat Sahari, Harvey S. Penefsky, Abdul-Kader Souid   +5 more
doaj  

Rapid detection of phosphine resistance in the lesser grain borer, Rhyzopertha dominica (Coleoptera: Bostrychidae) from China using ARMS-PCR

Julius-Kühn-Archiv, 2018
The lesser grain borer, Rhyzopertha dominica is one of the serious cosmopolitan stored grain pests worldwide. High phosphine resistant R. dominica has been reported in several countries.
Lu, Yujie, Zhang, Chenguang, Wang, Zhenyan, Yan, Xiaoping, Emery, Robert N.   +4 more
doaj   +1 more source

Virulence factors of Moraxella catarrhalis outer membrane vesicles are major targets for cross-reactive antibodies and have adapted during evolution [PDF]

, 2018
Moraxella catarrhalis is a common human respiratory tract pathogen. Its virulence factors associated with whole bacteria or outer membrane vesicles (OMVs) aid infection, colonization and may induce specific antibodies.
Augustyniak, Daria, Drulis-Kawa, Zuzanna, Mackiewicz, Paweł, McClean, Siobhán, Roszkowiak, Justyna, Roszniowski, Bartosz, Seredyński, Rafał, Smith, Darren   +7 more
core   +2 more sources

On the mechanism underlying tellurite reduction by Aeromonas caviae ST dihydrolipoamide dehydrogenase

Biochimie, 2014
The dihydrolipoamide dehydrogenase (LpdA) from the tellurite-resistant bacterium Aeromonas caviae ST reduces tellurite to elemental tellurium. To characterize this NADH-dependent activity, the A. caviae lpdA gene was subjected to site-directed mutagenesis and genes containing C45A, H322Y and E354K substitutions were individually transformed into ...
Mauricio Arenas-Salinas, Fabián A. Cornejo, Camilo A. Pinto, Felipe A. Arenas, Claudio C. Vásquez, W.A. Morales, C.A. Leal, Waldo A. Díaz-Vásquez, Waldo A. Díaz-Vásquez   +8 more
openaire   +7 more sources