Results 121 to 130 of about 9,017 (241)

Integrated Analysis of Cuproptosis Regulators Reveals Prognostic Significance and Therapeutic Targets in IDH1 Mutant Glioma

open access: yesMedComm – Future Medicine, Volume 4, Issue 1, March 2025.
This study performed a comprehensive analysis of cuproptosis‐related genes (CRGs) in IDH1‐mutant glioma samples from the TCGA database. Two novel IDH1‐mutant glioma subtypes were identified based on CRG expression patterns. FDX1 and SLC31A1 were identified as key regulators.
Yuxuan Luan   +6 more
wiley   +1 more source

Camelina circRNA landscape: Implications for gene regulation and fatty acid metabolism

open access: yesThe Plant Genome, Volume 18, Issue 1, March 2025.
Abstract Circular RNAs (circRNAs) are closed‐loop RNAs forming a covalent bond between their 3′ and 5′ ends, the back splice junction (BSJ), rendering them resistant to exonucleases and thus more stable compared to linear RNAs. Identification of circRNAs and distinction from their cognate linear RNA is only possible by sequencing the BSJ that is unique
Delecia Utley   +4 more
wiley   +1 more source

Another Target for NO [PDF]

open access: yes, 2011
Nitric oxide (NO) is a poisonous free radical made by phagocytic cells to combat pathogens. Richardson et al. (2011) show that the Salmonella enterica serovar Typhimurium lipoamide dehydrogenase is a target for the nitrosative stress exerted by NO and ...
Spiro, Stephen
core   +1 more source

Mechanism of reconstitution/activation of the soluble PQQ-dependent glucose dehydrogenase from Acinetobacter calcoaceticus: a comprehensive study [PDF]

open access: yesarXiv, 2019
The ability to switch on the activity of an enzyme through its spontaneous reconstitution has proven to be a valuable tool in fundamental studies of enzyme structure/reactivity relationships or in the design of artificial signal transduction systems in bioelectronics, synthetic biology, or bioanalytical applications.
arxiv  

Rapid detection of phosphine resistance in the lesser grain borer, Rhyzopertha dominica (Coleoptera: Bostrychidae) from China using ARMS-PCR

open access: yesJulius-Kühn-Archiv, 2018
The lesser grain borer, Rhyzopertha dominica is one of the serious cosmopolitan stored grain pests worldwide. High phosphine resistant R. dominica has been reported in several countries.
Lu, Yujie   +4 more
doaj   +1 more source

Do not forget interaction: Predicting fatality of COVID-19 patients using logistic regression [PDF]

open access: yesarXiv, 2020
Amid the ongoing COVID-19 pandemic, whether COVID-19 patients with high risks can be recovered or not depends, to a large extent, on how early they will be treated appropriately before irreversible consequences are caused to the patients by the virus. In this research, we reported an explainable, intuitive, and accurate machine learning model based on ...
arxiv  

On the mechanism underlying tellurite reduction by Aeromonas caviae ST dihydrolipoamide dehydrogenase

open access: yesBiochimie, 2014
The dihydrolipoamide dehydrogenase (LpdA) from the tellurite-resistant bacterium Aeromonas caviae ST reduces tellurite to elemental tellurium. To characterize this NADH-dependent activity, the A. caviae lpdA gene was subjected to site-directed mutagenesis and genes containing C45A, H322Y and E354K substitutions were individually transformed into ...
Mauricio Arenas-Salinas   +8 more
openaire   +7 more sources

Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species [PDF]

open access: yes, 2004
Mitochondria-produced reactive oxygen species (ROS) are thought to contribute to cell death caused by a multitude of pathological conditions. The molecular sites of mitochondrial ROS production are not well established but are generally thought to be ...
Beal, M. Flint   +6 more
core   +1 more source

Mitochondrial Oxygen Consumption by the Foreskin and its Fibroblast-rich Culture

open access: yesSultan Qaboos University Medical Journal, 2013
Objectives: This study investigated the feasibility of using a phosphorescence oxygen analyser to measure cellular respiration (mitochondrial O2 consumption) in foreskin samples and their fibroblast-rich cultures.Methods: Foreskin specimens from normal ...
Fatma Al-Jasmi   +5 more
doaj  

Human Pleural Fluid Elicits Pyruvate and Phenylalanine Metabolism in Acinetobacter baumannii to Enhance Cytotoxicity and Immune Evasion [PDF]

open access: yes, 2019
The CCAAT box-harboring proteins represent a family of heterotrimeric transcription factors which is highly conserved in eukaryotes. In fungi, one of the particularly important homologs of this family is the Hap complex that separates the DNA-binding ...
Bonomo, Robert A.   +15 more
core   +1 more source

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