Results 131 to 140 of about 9,017 (241)

Identification of potential biomarkers of cuproptosis in cerebral ischemia

Frontiers in Nutrition
ObjectiveCerebral ischemia can cause mild damage to local brain nerves due to hypoxia and even lead to irreversible damage due to neuronal cell death. However, the underlying pathogenesis of this phenomenon remains unclear.
Lihua Qin, Lihua Qin, Xi Cao, Tengjia Huang, Yixin Liu, Sheng Li   +5 more
doaj   +1 more source

Quantitative proteomics of a B12 -dependent alga grown in coculture with bacteria reveals metabolic tradeoffs required for mutualism [PDF]

, 2017
The unicellular green alga Lobomonas rostrata requires an external supply of vitamin B12 (cobalamin) for growth, which it can obtain in stable laboratory cultures from the soil bacterium Mesorhizobium loti in exchange for photosynthate.
Amin, Amin, Arrigo, Ashen, Beliaev, Bertrand, Bertrand, Biller, Bradford, Catalano, Chauvin, Cooper, Copley, Croft, Durham, Eisenreich, Elias, Emerich, Falkowski, Fernandes, Geng, González, Grant, Helliwell, Helliwell, Helliwell, Hold, Hom, Kanehisa, Kazamia, Kazamia, Koch, Koch, Liu, Lodwig, Lohse, Longworth, Matsuo, Maxwell, Mus, Nedelcu, Noirel, Ohlrogge, Paerl, Palmer, Pandhal, Panter, Park, Pfaffl, Saalbach, Saibil, Schmollinger, Shargool, Sher, Song, Tai, Thiel, Untergasser, Vizcaíno, Wagner-Döbler, Wienkoop, Xie, Zhang   +62 more
core   +2 more sources

Enzymatic Logic Gates with Noise-Reducing Sigmoid Response [PDF]

International Journal of Unconventional Computing 6, 451-460 (2010), 2009
Biochemical computing is an emerging field of unconventional computing that attempts to process information with biomolecules and biological objects using digital logic. In this work we survey filtering in general, in biochemical computing, and summarize the experimental realization of an AND logic gate with sigmoid response in one of the inputs.
arxiv  

The role of amino acids T148 and R281 in human dihydrolipoamide dehydrogenase

Journal of Biomedical Science, 2007
Human dihydrolipoamide dehydrogenase (hE3) is a common component of alpha-ketoacid dehydrogenase complexes. Mutations of this homodimeric protein cause E3 deficiency and are always fatal. To investigate its reaction mechanism, we first performed multiple sequence alignment with other 17 eukaryotic E3s.
Ling-Yun Chen, Ming-Chih Chou, Yi-Chun Wang, Pei-Ru Chen, Ted-Chung Liu, Shih-Tsung Wang, Wen-Hu Liu, Chuan Li   +7 more
openaire   +3 more sources

3-Hydroxyisobutyryl-CoA hydrolase involved in isoleucine catabolism regulates triacylglycerol accumulation in Phaeodactylum tricornutum [PDF]

, 2017
Since methylmalonyl-CoA epimerase appears to be absent in the majority of photosynthetic organisms, including diatoms, (S)-methylmalonyl-CoA, the intermediate of isoleucine (Ile) catabolism, cannot be metabolized to (R)methylmalonyl-CoA then to succinyl ...
Gong, Yangmin, Hu, Hanhua, Li, Xiaolong, Pan, Yufang, Yang, Juan   +4 more
core   +1 more source

Proteome- and Transcriptome-Driven Reconstruction of the Human Myocyte Metabolic Network and Its Use for Identification of Markers for Diabetes

Cell Reports, 2015
Skeletal myocytes are metabolically active and susceptible to insulin resistance and are thus implicated in type 2 diabetes (T2D). This complex disease involves systemic metabolic changes, and their elucidation at the systems level requires genome-wide ...
Leif Väremo, Camilla Scheele, Christa Broholm, Adil Mardinoglu, Caroline Kampf, Anna Asplund, Intawat Nookaew, Mathias Uhlén, Bente Klarlund Pedersen, Jens Nielsen   +9 more
doaj   +1 more source

Structural and Biochemical Investigation of Selected Pathogenic Mutants of the Human Dihydrolipoamide Dehydrogenase. [PDF]

Int J Mol Sci, 2023
Szabo E, Nemes-Nikodem E, Vass KR, Zambo Z, Zrupko E, Torocsik B, Ozohanics O, Nagy B, Ambrus A.   +8 more
europepmc   +1 more source

Purification and comparative studies of dihydrolipoamide dehydrogenases from the anaerobic, glycine-utilizing bacteria Peptostreptococcus glycinophilus, Clostridium cylindrosporum, and Clostridium sporogenes [PDF]

, 1990
D Dietrichs, Jan R. Andreesen
openalex   +1 more source

Dependence of Substrate Irradiation Reaction Rate Stimulation on Lactic Dehydrogenase Source [PDF]

arXiv, 2013
Stimulation of LDH initial reaction rates by timed pre-irradiation of crystalline sodium pyruvate and lithium lactate is reported for enzymes isolated from rabbit muscle, pig heart, human erythrocytes and chicken heart. The phenomenon investigated is referred to as the Comorosan effect.
arxiv  

Stimulation of Enzyme Reaction Rates by Crystalline Substrate Irradiation: Dependence on Identity of Irradiated Substance [PDF]

arXiv, 2013
The study reported here concerns a phenomenon, discovered and extensively investigated by Sorin Comorosan, wherein enzyme initial reaction rates are enhanced as a consequence of incorporation of solutions derived from previously irradiated crystalline material into the reaction medium.
arxiv