Results 41 to 50 of about 9,205 (218)

Variation in the organization and subunit composition of the mammalian pyruvate dehydrogenase complex E2/E3BP core assembly [PDF]

, 2011
The final version of this article is available at the link below.Crucial to glucose homoeostasis in humans, the hPDC (human pyruvate dehydrogenase complex) is a massive molecular machine comprising multiple copies of three distinct enzymes (E1–E3) and an
Alan Cooper, Blass, Brautigam, Brautigam, Chamberlain, Ciszak, Cooper, David Gilbert, Donna P. McGow, Frank, Hipps, Hiromasa, Hodgson, Hoyer, Huang, Izard, J. Gordon Lindsay, Jones, Jung, Konarev, Laue, Lessard, Leung, Lynch, Mande, Margaret A. Nutley, Mayers, McCartney, Olwyn Byron, Peter Kropholler, Philip Callow, Robinson, Sanderson, Schuck, Semenyuk, Smolle, Stanley, Stoops, Svergun, Swetha Vijayakrishnan, Vijayakrishnan, Wagenknecht, Yu, Zhou, Zhou   +44 more
core   +3 more sources

Mitochondrial Dihydrolipoamide Dehydrogenase is Upregulated in Response to Intermittent Hypoxic Preconditioning. [PDF]

Int J Med Sci, 2015
Intermittent hypoxia preconditioning (IHP) has been shown to protect neurons against ischemic stroke injury. Studying how proteins respond to IHP may identify targets that can help fight stroke. The objective of the present study was to investigate whether mitochondrial dihydrolipoamide dehydrogenase (DLDH) would respond to IHP and if so, whether such ...
Li R, Luo X, Wu J, Thangthaeng N, Jung ME, Jing S, Li L, Ellis DZ, Liu L, Ding Z, Forster MJ, Yan LJ.   +11 more
europepmc   +5 more sources

Development of Recombinant Dihydrolipoamide Dehydrogenase Subunit Vaccine against Vibrio Infection in Large Yellow Croaker

Fishes, 2022
Large yellow croaker (Larimichthys crocea), an economically important marine fish in China, has suffered from serious vibriosis, which has resulted in great economic losses for the large yellow croaker industry.
Xiaomeng Li, Yuanzhen Tan, Zheng Zhang, Yupeng Huang, Pengfei Mu, Zhengwei Cui, Xinhua Chen   +6 more
doaj   +1 more source

Richard Nelson Perham. 27 April 1937—14 February 2015 [PDF]

, 2018
Richard Nelson Perham, FRS, FMedSci, FRSA, was a British professor of structural biochemistry. He undertook his academic career at the University of Cambridge, holding positions as lecturer, reader, chair and head of the Department of Biochemistry, as ...
Charoy, François, Ferme, Vincenzo, Labba, Chahrazed, On the Move toMeaningful Internet Systems, Pautasso, Cesare, Rosinosky, Guillaume, Youcef, Samir   +6 more
core   +3 more sources

Human 2-Oxoglutarate Dehydrogenase Complex E1 Component Forms a Thiamin-derived Radical by Aerobic Oxidation of the Enamine Intermediate. [PDF]

, 2014
Herein are reported unique properties of the human 2-oxoglutarate dehydrogenase multienzyme complex (OGDHc), a rate-limiting enzyme in the Krebs (citric acid) cycle.
Ambrus, Attila, Gerfen, Gary, Nemeria, Natalia S., Patel, Hetalben, Tretter, László, Ádám, Veronika   +5 more
core   +4 more sources

Alterations of the mitochondrial proteome caused by the absence of mitochondrial DNA: A proteomic view [PDF]

, 2006
The proper functioning of mitochondria requires that both the mitochondrial and the nuclear genome are functional. To investigate the importance of the mitochondrial genome, which encodes only 13 subunits of the respiratory complexes, the mitochondrial ...
Abdul, Appleby, Armstrong, Bai, Bourges, Buchet, Chai, Claros, Da Cruz, Dey, Du, Garcia, Gianazza, Joseph, King, King, Lescuyer, Luche, Manjasetty, Martinus, Perkins, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Santoni, Sharma, Sharp, Sherer, Singh, Sinha, Suzuki, Tastet, Taylor, Tryoen-Toth, Ugalde, Wiedemann, Zamzami, Zischka   +39 more
core   +4 more sources

Characterization and epitope mapping of human monoclonal antibodies to PDC-E2, the immunodominant autoantigen of primary biliary cirrhosis [PDF]

, 1992
Further to define the epitopes of PDC-E2, the major autoantigen in primary biliary cirrhosis (PBC), we have developed and characterized five human monoclonal antibodies. These antibodies were derived by fusing a regional hepatic lymph node from a patient
Bassendine, Baum, Casali, Chambers, Coppel, Coppel, Cram, Flannery, Fregeau, Fregeau, Fujikura, Fusey, Fussey, Gershwin, Gershwin, Griffin, Griffin, James, Kaplan, Kunicki, Larrick, Leung, Leung, Mackay, Mackay, Mathews, McNeilage, Okamoto, Pollack, Ramsden, Reeves, Reimer, Robbins, Rokeach, Rowley, Ruther, Salemuddin, Sturgess, Sudin, Surh, Surh, Surh, Surh, Tan, Uibo, Van de Water, Van de Water, Van de Water, Van de Water, Williams   +49 more
core   +1 more source

Label-free shotgun proteomics and metabolite analysis reveal a significant metabolic shift during citrus fruit development. [PDF]

, 2011
Label-free LC-MS/MS-based shot-gun proteomics was used to quantify the differential protein synthesis and metabolite profiling in order to assess metabolic changes during the development of citrus fruits.
Blumwald, Eduardo, Boo, Kyung Hwan, Eigenheer, Richard A, Katz, Ehud, Kim, Ho Youn, Negre-Zakharov, Florence, Phinney, Brett S, Sadka, Avi, Shulaev, Vladimir   +8 more
core   +3 more sources

Flavoprotein-mediated tellurite reduction: structural basis and applications to the synthesis of tellurium-containing nanostructures

Frontiers in Microbiology, 2016
The tellurium oxyanion tellurite (TeO32-) is extremely harmful for most organisms. It has been suggested that a potential bacterial tellurite resistance mechanism would consist of an enzymatic, NAD(P)H-dependent, reduction to the less toxic form ...
Mauricio Arenas-Salinas, Joaquín Ignacio Vargas, Wladimir Morales, Camilo Pinto, Pablo Muñoz, Fabian Alexis Cornejo, Benoit Pugin, Juan Sandoval, Waldo Diaz, Claudia Muñoz-Villagrán, Fernanda Jimena Rodríguez, Eduardo Morales, Claudio Christian Vásquez, Felipe Arenas   +13 more
doaj   +1 more source

Formation of reactive oxygen species by human and bacterial pyruvate and 2- oxoglutarate dehydrogenase multienzyme complexes reconstituted from recombinant components [PDF]

, 2015
Individual recombinant components of pyruvate and 2-oxoglutarate dehydrogenase multienzyme complexes (PDHc, OGDHc) of human and Escherichia coli (E. coli) origin were expressed and purified from E. coli with optimized protocols.
Adam-Vizi, Adam-Vizi, Adam-Vizi, Ambrus, Ambrus, Ambrus, Ambrus, Ambrus, Andreyev, Attila Ambrus, Azzi, Babady, Balakrishnan, Bando, Beata Torocsik, Berg, Blass, Brautigam, Brautigam, Brown, Bunik, Bunik, Cameron, Chinopoulos, Chinopoulos, Constantinescu, Contreras, Cruts, Diaz-Munoz, Droge, Dumont, Erfle, Fisher-Wellman, Frank, Frank Jordan, Gazaryan, Gibson, Gibson, Gibson, Gibson, Graf, Guest, Gupta, Hamada, Hansford, Harris, Hirashima, Hong, Huennekens, Kiselevsky, Klyachko, Koike, Koike, Korotchkina, Korotchkina, Kumar, Kussmaul, Lai, Lakaschus, Laszlo Tretter, Martinvalet, Massey, Massey, Massey, Mattias Nilsson, Mayo, McCord, McLennan, Mottley, Nakano, Natalia S. Nemeria, Nemeria, Nemeria, Nemeria, Nulton-Persson, Otulakowski, Patel, Perham, Pettit, Popov, Poulsen, Quinlan, Quinonez, Reed, Reed, Reed, Reed, Rosen, Saumweber, Seifert, Shaag, Shany, Sheu, Shi, Shim, Siebels, Song, Starkov, Starkov, Starkov, Tahara, Thekkumkara, Tretter, Tretter, Tretter, Tretter, Tretter, Tretter, Tretter, Tretter, Tretter, Tretter, Tretter, Tretter, Tyagi, Vaubel, Vera Adam-Vizi, Vereczki, Wei, Willems, Yan, Yang, Yi, Zundorf   +123 more
core   +1 more source