Results 81 to 90 of about 297,107 (242)

The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase. [PDF]

, 1988
Autoantibodies to mitochondrial antigens are characteristic of the autoimmune liver disease primary biliary cirrhosis (PBC), but the precise antigenic determinants recognized by these antibodies have not been defined.
Ansari, A, Coppel, R, Gershwin, M, Leung, P, Van De Water, Judith   +4 more
core  

Accessing the genomic information of unculturable oceanic picoeukaryotes by combining multiple single cells [PDF]

, 2017
Mangot, Jean-François et al.-- 12 pages, 7 figures, 2 tables, supplementary information https://dx.doi.org/10.1038/srep41498Pico-sized eukaryotes play key roles in the functioning of marine ecosystems, but we still have a limited knowledge on their ...
Latorre, Fran, Logares, Ramiro, Mangot, Jean-François, Massana, Ramon, Sánchez, Pablo   +4 more
core   +1 more source

Thioredoxins o1 and h2 jointly adjust mitochondrial dihydrolipoamide dehydrogenase-dependent pathways towards changing environments.

Plant, Cell and Environment
Thioredoxins (TRXs) are central to redox regulation, modulating enzyme activities to adapt metabolism to environmental changes. Previous research emphasized mitochondrial and microsomal TRX o1 and h2 influence on mitochondrial metabolism, including ...
S. Timm, Nicole Klaas, Jan Niemann, Kathrin Jahnke, S. Alseekh, You-Qing Zhang, Paulo V. L. Souza, L. Hou, Maike Cosse, Jennifer Selinski, P. Geigenberger, Danilo M. Daloso, A. Fernie, Martin Hagemann   +13 more
semanticscholar   +1 more source

Evaluation of Shifts of Gene Transcription Levels of Unicellular Green Alga Chlamydomonas reinhardtii Due to UV-C Irradiation

Microorganisms, 2023
Green algae produce valuable lipids as carbon-recycling resources. Collecting whole cells with the intracellular lipids could be efficient without cell burst; however, direct use of the cells causes microbial contamination in environments.
Akihito Nakanishi, Nanami Ozawa, Masahiko Watanabe   +2 more
doaj   +1 more source

Transcriptional and Proteomic Analysis of a Ferric Uptake Regulator (Fur) Mutant of Shewanella oneidensis: Possible Involvement of Fur in Energy Metabolism, Transcriptional Regulation, and Oxidative Stress [PDF]

, 2002
The iron-directed, coordinate regulation of genes depends on the fur (ferric uptake regulator) gene product, which acts as an iron-responsive, transcriptional repressor protein. To investigate the biological function of a fur homolog in the dissimilatory
Beliaev, Alexander S., Brandt, Craig C., Giometti, Carol S., Khare, Tripti, Lies, Douglas P., Lim, Hanjo, Nealson, Kenneth H., Thompson, Dorothea K., Tiedje, James M., Tollaksen, Sandra L., Yates, John, III, Zhou, Jizhong   +11 more
core   +2 more sources

Metabolism‐Regulating Nanomedicines for Cancer Therapy

Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley   +1 more source

TLR4 Agonist Combined with Trivalent Protein JointS of Streptococcus suis Provides Immunological Protection in Animals

Vaccines, 2021
Streptococcus suis (S. suis) serotype 2 (SS2) is the causative agent of swine streptococcosis and can cause severe diseases in both pigs and humans. Although the traditional inactive vaccine can protect pigs from SS2 infection, novel vaccine candidates ...
Zhaofei Wang, Mengting Guo, Licheng Kong, Ya Gao, Jingjiao Ma, Yuqiang Cheng, Henan Wang, Yaxian Yan, Jianhe Sun   +8 more
doaj   +1 more source

Transcriptomic Responses of the Marine Diatom Phaeodactylum tricornutum to High Carbon and Low Nitrogen Stress

Ecology and Evolution, Volume 16, Issue 1, January 2026.
To elucidate the integrated transcriptional mechanisms underlying diatom acclimation to coupled carbon–nitrogen (CN) imbalance, we employed RNA sequencing (RNA‐Seq) to characterize the global transcriptional response of the model diatom Phaeodactylum tricornutum to high CO2 (~2000 μatm) and low nitrogen (10% of nitrogen concentration in f/2 medium ...
Yi Zhang, Jiawen Duan, Yimeng Zheng, Xiaoqi Chen, Chenhui Li, Zhenyu Xie, Aiyou Huang   +6 more
wiley   +1 more source

Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation

Cell Reports, 2018
Summary: Dendritic cell (DC) maturation induced by Toll-like receptor agonists requires activation of downstream signal transduction and metabolic changes. The endogenous metabolite citrate has recently emerged as a modulator of DC activation.
Kazuhito Gotoh, Takafumi Morisaki, Daiki Setoyama, Katsuhiko Sasaki, Mikako Yagi, Ko Igami, Soichi Mizuguchi, Takeshi Uchiumi, Yoshinori Fukui, Dongchon Kang   +9 more
doaj   +1 more source

From identification of fluorescent flavoproteins to mitochondrial redox indicators in intact tissues [PDF]

Journal of Innovative Optical Health Sciences, 2014
Development of the use of flavin and nicotinamide-adenine nucleotide fluorescence in monitoring the redox state of the free mitochondrial NADH/NAD+ couple in cells, tissues and organs is reviewed.
Ilmo E. Hassinen
doaj   +1 more source