Results 51 to 60 of about 3,572 (156)

Global gene-expression analysis of the response of Salmonella Enteritidis to egg-white exposure reveals multiple egg-white-imposed stress responses [PDF]

, 2017
Chicken egg white protects the embryo from bacterial invaders by presenting an assortment of antagonistic activities that combine together to both kill and inhibit growth. The key features of the egg-white anti-bacterial system are iron restriction, high
Alabdeh, Mariah, Andrews, Simon C., Baron, Florence, Bonnassie, Sylvie, Cochet, Marie-Françoise, Gautier, Michel, Guérin-Dubiard, Catherine, Jan, Sophie, Nau, Françoise   +8 more
core   +2 more sources

Pyruvate dehydrogenase deficiency: morphological and metabolic effects, creation of animal model to search for curative treatment [PDF]

, 2020
The main source of energy for brain and other organs is glucose. To obtain energy for all tissue, glucose has to come through glycolysis; then as pyruvate it is converted to acetyl-CoA by pyruvate dehydrogenase complex (PDC) and finally enters citric ...
Ebertowska, A., Klejbor, I., Ludkiewicz, B., Melka, N., Moryś, J.   +4 more
core   +2 more sources

The Immune Microenvironment in Liver Cancer: From Analysis to Targeting

Advanced Science, Volume 12, Issue 47, December 18, 2025.
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan, Hao Li, Jian Xue, Yourong Duan, Jin Sun, Meng Niu   +5 more
wiley   +1 more source

Effects of salinity on the transcriptome of growing maize leaf cells point at cell-age specificity in the involvement of the antioxidative response in cell growth restriction [PDF]

, 2013
BACKGROUND: Salinity inhibits growth and development of most plants. The response to salinity is complex and varies between plant organs and stages of development. It involves challenges of ion toxicities and deficiencies as well as osmotic and oxidative
Michael Kravchik, Nirit Bernstein
core   +1 more source

Mechanism and role of regulated cell death in tumor immunity and immunotherapy

Cancer Communications, Volume 45, Issue 11, Page 1456-1495, November 2025.
Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu, Yan Li, Bingjie Lian, Yitao Mao, Luqing Zhao   +4 more
wiley   +1 more source

Characterization of the Arabidopsis thaliana 2-Cys peroxiredoxin interactome [PDF]

, 2016
This document is the Accepted Manuscript of the following article: Delphine Cerveau, et al, ‘Characterization of the Arabidopsis thaliana 2-Cys peroxiredoxin interactome’, Plant Science, Vol. 252, pp.
Ahn, Alexandra Kraut, Awad, Baier, Baier, Balmer, Balmer, Balmer, Broin, Broin, Cai, Caporaletti, Cerveau, Chae, Chaturvedi, Chen, Chen, Chew, Cho, Coic, Collin, Dangoor, Day, Delphine Cerveau, Dietz, Dietz, Dietz, Dixon, Dixon, Dominguez-Solis, Eliyahu, Grant, Gutierrez-Marcos, Halliwell, Hattenbach, Henrik U. Stotz, Heukeshoven, Hong, Hudson, Jang, Johnston, Jung, Jönsson, Kim, Kim, Kim, Kojima, König, Lamkemeyer, Laxa, Lee, Lemaire, Liebthal, Lindhal, Maeda, Marchand, Martin J. Mueller, Montrichard, Moon, Moon, Motohashi, Muhlbach, Muthuramalingam, Pascal Rey, Peltier, Perez-Ruiz, Phee, Puerto-Galan, Pulido, Qu, Ralat, Reed, Rey, Rey, Rey, Rhee, Richter, Sahrawy, Schürmann, Setya, Sirpio, Song, Stenbaek, Vizcaíno, Wagner, Whitney, Wong, Woo, Wood, Yamauchi, Yamauchi, Yohann Couté, Yu   +92 more
core   +4 more sources

Novel mutations in a boy with dihydrolipoamide dehydrogenase deficiency.

Medical science monitor : international medical journal of experimental and clinical research, 2002
Dihydrolipoamide dehydrogenase (DLD) deficiency is a rare cause of primary lactic acidosis in infancy.This article presents the results of biochemical and molecular analyses and metabolic response to treatment procedures in a 10-week old boy presenting with vomiting, progressive hypotonia, lactic acidosis (pH 7.04; BE - 20; B-lactate 6.6 mmol/l ...
L, Cerna, L, Wenchich, H, Hansiková, S, Kmoch, K, Peskova, P, Chrastina, J, Brynda, J, Zeman   +7 more
openaire   +1 more source

Foetal disruptive brain injuries: Diagnosing the underlying pathogenetic mechanisms with cranial ultrasonography

Developmental Medicine &Child Neurology, Volume 67, Issue 11, Page 1383-1408, November 2025.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16431 Abstract Antenatal destructive events affecting the central nervous system of the foetus lead to disruptive brain lesions that are often associated with impaired neurodevelopment.
Ana Alarcón, Nuria Carreras, Tobias Muehlbacher, Dídac Casas‐Alba, Roberta Arena, Paola Roca‐Llabrés, Juan Navarro‐Morón, Linda S. de Vries, Paul Govaert, the EurUS.Brain group, Thais Agut, Roberta Arena, Ana Alarcón, Juan Arnáez, Marco Bartocci, Isabel Benavente‐Fernández, María Carmen Bravo, Fernando Cabañas, Nuria Carreras, Olivier Claris, Jeroen Dudink, Monica Fumagalli, Alfredo García‐Alix, Paul Govaert, Sandra Horsch, Simón Lubián, Tobias Muehlbacher, Alessandro Parodi, Adelina Pellicer, Luca Ramenghi, Charles C. Roehr, Simone Schwarz, Sylke Steggerda, Eva Valverde   +33 more
wiley   +1 more source

dldhcri3 zebrafish exhibit altered mitochondrial ultrastructure, morphology, and dysfunction partially rescued by probucol or thiamine

JCI Insight
Dihydrolipoamide dehydrogenase (DLD) deficiency is a recessive mitochondrial disease caused by variants in DLD, the E3 subunit of mitochondrial α-keto (or 2-oxo) acid dehydrogenase complexes.
Manuela Lavorato, Donna Iadarola, Cristina Remes, Prabhjot Kaur, Chynna Broxton, Neal D. Mathew, Rui Xiao, Christoph Seiler, Eiko Nakamaru-Ogiso, Vernon E. Anderson, Marni J. Falk   +10 more
doaj   +1 more source

Complementary Muscle Metabolomics and Proteomics of Muscle in Cows With Post‐Calving Ketosis

Journal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
ABSTRACT Background The muscle tissue of dairy cows is a site of β‐hydroxybutyrate (BHBA) metabolism. The mechanisms underlying the changes in proteins and metabolites in the muscle tissue of cows with ketosis remain unclear. Objectives To elucidate the metabolic and physiological molecular adaptation mechanisms in the muscle tissue of cows with ...
Tao Tang, Jing Zhou, Jiahao Shao, Meigui Wang, Siqi Xia, Wenqiang Sun, Xianbo Jia, Jie Wang, Songjia Lai   +8 more
wiley   +1 more source