Biomarker discovery for asthma phenotyping: From gene expression to the clinic [PDF]
Asthma is considered a complex respiratory disease of which various asthma phenotypes are being discovered. Clinical biomarkers have shown to be successful in the management of asthma phenotypes.
Wagener, A.H.
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Screening and validating genes associated with cuproptosis in systemic lupus erythematosus by expression profiling combined with machine learning [PDF]
Cell death has long been a focal point in life sciences research, and recently, scientists have discovered a novel form of cell death induced by copper, termed cuproptosis.
Cheng, Ruoying +4 more
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Immunological and biosynthetic studies of the human pyruvate dehydrogenase complex [PDF]
The human pyruvate dehydrogenase multi-enzyme complex (PDC) catalyses the oxidative decarboxylation of pyruvate, transferring the resultant acetyl group to coenzyme A.
Al-Amodi, Hiba Saeed Bagader
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Biogenesis of Organelles and Membrane Proteins. [PDF]
Harmey, Matthew A. +3 more
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Dynamics of Adaptive Microevolution of Hypermutable Pseudomonas aeruginosa during Chronic Pulmonary Infection in Patients with Cystic Fibrosis [PDF]
Eichner, Anja +7 more
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Antigenically dominant proteins within the human liver mitochondrial proteome identified by monoclonal antibodies [PDF]
FuChu He +13 more
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Diet-Sensitive Sources of Reactive Oxygen Species in\ud Liver Mitochondria: Role of Very Long Chain Acyl-CoA\ud Dehydrogenases [PDF]
High fat diets and accompanying hepatic steatosis are highly prevalent conditions. Previous work has shown that\ud steatosis is accompanied by enhanced generation of reactive oxygen species (ROS), which may mediate further liver\ud damage.
Cardoso, Ariel Rodrigues +2 more
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The architectural complexity of the human PDC core assembly [PDF]
The mammalian pyruvate dehydrogenase complex (PDC) is a key multi-enzyme assembly linking the glycolytic pathway to the TCA cycle via the specific conversion of pyruvate to acetyl CoA and, as such, is responsible for the maintenance of glucose ...
Vijayakrishnan, Swetha
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A mitochondrial machinery for membrane translocation of precursor proteins [PDF]
Neupert, Walter, Pfanner, Nikolaus
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Thiamine and the Cellular Energy Cycles — A Novel Perspective on Type 2 Diabetes Treatment [PDF]
Alam, Saadia Shahzad, Riaz, Samreen
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