Results 1 to 10 of about 1,196 (125)

Unaltered maximal power and submaximal performance correlates with an oxidative vastus lateralis proteome phenotype during tapering in male cyclists. [PDF]

Physiol Rep
Abstract Little is known on how a short‐term reduction of training volume changes muscle proteome and physiological parameters. We investigated the impact of halving training volume during regular training of cyclists on physiological parameters in relation to vastus lateralis protein profiles and fiber percentage ratios. Fifteen male cyclists (age: 30.
de Lange P, Petito G, Notbohm HL, Giacco A, Renzone G, Silvestri E, Cuomo A, Suhr F, Schiffer T, Zacher J, Cioffi F, Senese R, Scaloni A, Schumann M, Bloch W.   +14 more
europepmc   +2 more sources

Transcriptome-Wide Association Analysis of Flavonoid Biosynthesis Genes and Their Correlation With Leaf Phenotypes in Hawk Tea (Litsea coreana var. sinensis). [PDF]

Ecol Evol
A total of 84 significant SNPs related to flavonoid content were identified through transcriptome‐wide association analysis, and 13 SNPs located within gene regions were identified as structural genes primarily implicated in metabolic processes and the biosynthesis of secondary metabolites. ABSTRACT Hawk tea (Litsea coreana var. sinensis), derived from
Yang L, Li H, Xie N, Yuan G, Guo Q.
europepmc   +2 more sources

Interventional‐ and amputation‐stage muscle proteomes in the chronically threatened ischemic limb

Clinical and Translational Medicine, Volume 12, Issue 1, January 2022., 2022
Proteomic analyses of CLTI muscle specimens identify a distinct limb muscle proteome signature characterized by a severe mitochondriopathy in amputation‐stage specimens, which was discovered to differ from non‐PAD controls and CLTI pre‐surgical intervention limb muscles.
Terence E. Ryan, Kyoungrae Kim, Salvatore T. Scali, Scott A. Berceli, Trace Thome, Zachary R. Salyers, Kerri A. O'Malley, Thomas D. Green, Reema Karnekar, Kelsey H. Fisher‐Wellman, Dean J. Yamaguchi, Joseph M. McClung   +11 more
wiley   +1 more source

Dissecting the phenotypic components and genetic architecture of maize stem vascular bundles using high‐throughput phenotypic analysis

Plant Biotechnology Journal, Volume 19, Issue 1, Page 35-50, January 2021., 2021
Summary High‐throughput phenotyping is increasingly becoming an important tool for rapid advancement of genetic gain in breeding programmes. Manual phenotyping of vascular bundles is tedious and time‐consuming, which lags behind the rapid development of functional genomics in maize.
Ying Zhang, Jinglu Wang, Jianjun Du, Yanxin Zhao, Xianju Lu, Weiliang Wen, Shenghao Gu, Jiangchuan Fan, Chuanyu Wang, Sheng Wu, Yongjian Wang, Shengjin Liao, Chunjiang Zhao, Xinyu Guo   +13 more
wiley   +1 more source

TMT‐Based Quantitative Proteomics Analysis of the Fish‐Borne Spoiler Shewanella putrefaciens Subjected to Cold Stress Using LC‐MS/MS

Journal of Chemistry, Volume 2021, Issue 1, 2021., 2021
Shewanella putrefaciens is a specific spoilage bacterium for fish during cold storage. To better understand the molecular mechanisms of cold stress adaptation of S. putrefaciens, tandem mass tag‐ (TMT‐) based quantitative proteomic analysis was performed to detect the effects of cold stress on protein expression profiles in S.
Xin Gao, Peiyun Li, Jun Mei, Jing Xie, Ajaya Kumar Singh   +4 more
wiley   +1 more source

Genomics Analysis of Metabolic Pathways of Human Stem Cell‐Derived Microglia‐Like Cells and the Integrated Cortical Spheroids

Stem Cells International, Volume 2019, Issue 1, 2019., 2019
Brain spheroids or organoids derived from human pluripotent stem cells (hiPSCs) are still not capable of completely recapitulating in vivo human brain tissue, and one of the limitations is lack of microglia. To add built‐in immune function, coculture of the dorsal forebrain spheroids with isogenic microglia‐like cells (D‐MG) was performed in our study.
Julie Bejoy, Xuegang Yuan, Liqing Song, Thien Hua, Richard Jeske, Sébastien Sart, Qing-Xiang Amy Sang, Yan Li, Monica Montesi   +8 more
wiley   +1 more source

Prediabetes Induced by Fructose‐Enriched Diet Influences Cardiac Lipidome and Proteome and Leads to Deterioration of Cardiac Function prior to the Development of Excessive Oxidative Stress and Cell Damage

Oxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019
Prediabetes is a condition affecting more than 35% of the population. In some forms, excessive carbohydrate intake (primarily refined sugar) plays a prominent role. Prediabetes is a symptomless, mostly unrecognized disease which increases cardiovascular risk.
Gergő Szűcs, Andrea Sója, Mária Péter, Márta Sárközy, Bella Bruszel, Andrea Siska, Imre Földesi, Zoltán Szabó, Tamás Janáky, László Vígh, Gábor Balogh, Tamás Csont, Konstantin Lyamzaev   +12 more
wiley   +1 more source

A Liquid Chromatography with Tandem Mass Spectrometry‐Based Proteomic Analysis of Primary Cultured Cells and Subcultured Cells Using Mouse Adipose‐Derived Mesenchymal Stem Cells

Stem Cells International, Volume 2019, Issue 1, 2019., 2019
Adipose‐derived mesenchymal stem cells (MSC‐ATs) are representative cell sources for cell therapy. However, how cell stress resulting from passage influences the MSC‐AT protein expression has been unclear. In this study, a protein expression analysis was performed by liquid chromatography with tandem mass spectrometry (LC‐MS/MS) using mouse primary ...
Yoshiki Nakashima, Saifun Nahar, Chika Miyagi-Shiohira, Takao Kinjo, Naoya Kobayashi, Issei Saitoh, Masami Watanabe, Jiro Fujita, Hirofumi Noguchi, Katia Mareschi   +9 more
wiley   +1 more source

A high‐fat diet impairs mitochondrial biogenesis, mitochondrial dynamics, and the respiratory chain complex in rat myocardial tissues

Journal of Cellular Biochemistry, Volume 119, Issue 11, Page 9602-9602, November 2018., 2018
Abstract A high‐fat diet (HFD) has been associated with heart failure and arrhythmias; however, the molecular mechanisms underlying these associations are poorly understood. The mitochondria play an essential role in optimal heart performance, most of the energy for which is obtained from the oxidation of fatty acids.
Dan Chen, Xia Li, LiTing Zhang, Mei Zhu, Ling Gao   +4 more
wiley   +1 more source

The Isoquinoline Alkaloid Dauricine Targets Multiple Molecular Pathways to Ameliorate Alzheimer‐Like Pathological Changes In Vitro

Oxidative Medicine and Cellular Longevity, Volume 2018, Issue 1, 2018., 2018
Alzheimer’s disease (AD), the most common neurodegenerative disease, has no effective treatment. Dauricine (DAU), a benzyl tetrahydroisoquinoline alkaloid isolated from the root of Menispermum dauricum DC, reportedly has neuroprotective effects in cerebral ischemia.
Pan Liu, Xiao Chen, Haizhe Zhou, Liqun Wang, Zaijun Zhang, Xiaohu Ren, Feiqi Zhu, Yi Guo, Xinfeng Huang, Jianjun Liu, Peter S. Spencer, Xifei Yang, Lisbell Estrada   +12 more
wiley   +1 more source