Results 21 to 30 of about 1,285 (110)
An in vitro model of murine middle ear epithelium. [PDF]
, 2016 Otitis media (OM) or middle ear inflammation is the most common pediatric disease and leads to significant morbidity. Although understanding of underlying disease mechanisms is hampered by complex pathophysiology it is clear that epithelial abnormalities
Admyre +73 more
core +3 more sources
Identification of metabolism pathways directly regulated by sigma54 factor in Bacillus thuringiensis [PDF]
, 2015 Sigma54 (σ54) normally regulates nitrogen and carbon utilization in bacteria. Promoters that are σ54-dependent are highly conserved and contain short sequences located at the −24 and −12 positions upstream of the transcription initiation site.
Fuping Song +4 more
core +2 more sources
Stem Cells International, Volume 2019, Issue 1, 2019., 2019 Brain spheroids or organoids derived from human pluripotent stem cells (hiPSCs) are still not capable of completely recapitulating in vivo human brain tissue, and one of the limitations is lack of microglia. To add built‐in immune function, coculture of the dorsal forebrain spheroids with isogenic microglia‐like cells (D‐MG) was performed in our study.
Julie Bejoy +8 more
wiley +1 more source
The relative abundance of APOE and Aβ1-42 associated with abnormal prion protein differs between Creutzfeldt-Jakob disease subtypes [PDF]
, 2016 Aggregated and protease-resistant mammalian prion protein (PrPSc) is the primary protein component of infectious prions. Enriched PrPSc preparations are often used to study the mechanisms that underly prion disease.
Choi, Young Pyo +7 more
core +4 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma +12 more
wiley +1 more source
Oxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019 Prediabetes is a condition affecting more than 35% of the population. In some forms, excessive carbohydrate intake (primarily refined sugar) plays a prominent role. Prediabetes is a symptomless, mostly unrecognized disease which increases cardiovascular risk.
Gergő Szűcs +12 more
wiley +1 more source
The effect of mucA allele on biofilm architecture and the biofilm-related proteomes [PDF]
, 2011 In this study, a unique mucA mutation (designated mucA56) was introduced, which was characterized by deletion of bases 166-333, encoding MucA56 protein with the deletion of the trans-membrane region, which then was proved to be cytoplasmic with phoA-mucA
Chen, Anqun +3 more
core
Stem Cells International, Volume 2019, Issue 1, 2019., 2019 Adipose‐derived mesenchymal stem cells (MSC‐ATs) are representative cell sources for cell therapy. However, how cell stress resulting from passage influences the MSC‐AT protein expression has been unclear. In this study, a protein expression analysis was performed by liquid chromatography with tandem mass spectrometry (LC‐MS/MS) using mouse primary ...
Yoshiki Nakashima +9 more
wiley +1 more source
Membrane proteomic analysis of pancreatic cancer cells [PDF]
, 2010 Background Pancreatic cancer is one of the most aggressive human tumors due to its high potential of local invasion and metastasis. The aim of this study was to characterize the membrane proteomes of pancreatic ductal adenocarcinoma (PDAC) cells of ...
Go, Vay Liang W +3 more
core +4 more sources
Developmental Medicine &Child Neurology, Volume 67, Issue 11, Page 1383-1408, November 2025.Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16431 Abstract Antenatal destructive events affecting the central nervous system of the foetus lead to disruptive brain lesions that are often associated with impaired neurodevelopment.
Ana Alarcón +33 more
wiley +1 more source