Serum DLAT Is a Potential Diagnostic Marker in AFP-Negative HCC.
The aim of this study was to analyze dihydrolipoyllysine-residue acetyltransferase (DLAT) expression and diagnostic ability in hepatocellular carcinoma (HCC), assess its role in HCC growth, and factors affecting it.
Fangfang Huang+4 more
semanticscholar +1 more source
eIF5A (eukaryotic translation initiation factor 5A) is the only cellular protein containing hypusine [Nϵ-(4-amino-2-hydroxybutyl)lysine]. eIF5A is activated by the post-translational synthesis of hypusine and the hypusine modification is essential for ...
Seung Bum Lee+7 more
semanticscholar +1 more source
Supplementary material for the article: Izrael-Živković, L.; Rikalović, M.; Gojgić-Cvijović, G.; Kazazić, S.; Vrvić, M.; Brčeski, I.; Beškoski, V.; Lončarević, B.; Gopčević, K.; Karadžić, I. Cadmium Specific Proteomic Responses of a Highly Resistant: Pseudomonas Aeruginosa San Ai. RSC Advances 2018, 8 (19), 10549–10560. https://doi.org/10.1039/c8ra00371h [PDF]
Supplementary material for: [https://doi.org/10.1039/c8ra00371h]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789 ...
Beškoski, Vladimir+9 more
core +2 more sources
Direct in-gel fluorescence detection and cellular imaging of O-GlcNAc-modified proteins [PDF]
We report an advanced chemoenzymatic strategy for the direct fluorescence detection, proteomic analysis, and cellular imaging of O-GlcNAc-modified proteins.
Agnew, Brian J.+7 more
core +1 more source
Significance Post-translational modification is crucial for regulating protein function. Acetylation of N-terminal residues is a major form of post-translational modification, but the functions of N-terminal acetyltransferases in vivo are not well ...
Jung-Wan Mok, Kwang-Wook Choi
semanticscholar +1 more source
Brain spheroids or organoids derived from human pluripotent stem cells (hiPSCs) are still not capable of completely recapitulating in vivo human brain tissue, and one of the limitations is lack of microglia. To add built‐in immune function, coculture of the dorsal forebrain spheroids with isogenic microglia‐like cells (D‐MG) was performed in our study.
Julie Bejoy+8 more
wiley +1 more source
Genetic response to metabolic fluctuations: correlation between central carbon metabolism and DNA replication in Escherichia coli [PDF]
BACKGROUND: Until now, the direct link between central carbon metabolism and DNA replication has been demonstrated only in Bacillus. subtilis. Therefore, we asked if this is a specific phenomenon, characteristic for this bacterium and perhaps for its ...
Agnieszka Szalewska-Pałasz+4 more
core +2 more sources
Prediabetes is a condition affecting more than 35% of the population. In some forms, excessive carbohydrate intake (primarily refined sugar) plays a prominent role. Prediabetes is a symptomless, mostly unrecognized disease which increases cardiovascular risk.
Gergő Szűcs+12 more
wiley +1 more source
Adipose‐derived mesenchymal stem cells (MSC‐ATs) are representative cell sources for cell therapy. However, how cell stress resulting from passage influences the MSC‐AT protein expression has been unclear. In this study, a protein expression analysis was performed by liquid chromatography with tandem mass spectrometry (LC‐MS/MS) using mouse primary ...
Yoshiki Nakashima+9 more
wiley +1 more source
ABHD11 maintains 2-oxoglutarate metabolism by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex [PDF]
: 2-oxoglutarate (2-OG or α-ketoglutarate) relates mitochondrial metabolism to cell function by modulating the activity of 2-OG dependent dioxygenases involved in the hypoxia response and DNA/histone modifications.
Antrobus, Robin+8 more
core +4 more sources