Study on the Metabonomics Mechanism of Mongolian Medical Andai Therapy on Healthy People
Andai therapy is a traditional therapy combining body, mind, and language with Mongolian characteristics. In the form of singing and dancing, it is widely popular among people of all ages in Mongolian areas of Inner Mongolia. According to Mongolian medicine, Heyi is one of the three elements of human body, and it can maintain life activities, promote ...
QiLa Sa +5 more
wiley +1 more source
Mechanism of Synsepalum dulcificum Daniell. Inhibiting Lung Adenocarcinoma
Objective: Synsepalum dulcificum Daniell. (SD) is a natural plant fruit and is famous for containing miraculin. It has been reported that SD can be used as an adjuvant treatment to correct patients’ loss of taste during the antitumor process, but the effect of SD itself as an antitumor is not clear.
Qi Chen +7 more
wiley +1 more source
Pharmacogenomics of anticancer drugs: Personalising the choice and dose to manage drug response
The field of pharmacogenomics has made great strides in oncology over the last 20 years and indeed a significant number of pre‐emptive genetic tests are now routinely undertaken prior to anticancer drug administration. Many of these gene–drug interactions are the fruits of candidate gene and genome‐wide association studies, which have largely focused ...
Daniel F. Carr +2 more
wiley +1 more source
Uridine Metabolism and Its Role in Glucose, Lipid, and Amino Acid Homeostasis
Pyrimidine nucleoside uridine plays a critical role in maintaining cellular function and energy metabolism. In addition to its role in nucleoside synthesis, uridine and its derivatives contribute to reduction of cytotoxicity and suppression of drug‐induced hepatic steatosis.
Yumei Zhang +4 more
wiley +1 more source
EFFECTS OF CERTAIN DRUGS ON DIHYDROPYRIMIDINE DEHYDROGENASE ENZYME PURIFIED FROM BOVINE LIVER
The inhibitory effects of certain drugs on dihydropyrimidine dehydrogenase from the bovine liver have been investigated. Dihydropyrimidine dehydrogenase [5, 6-dihydrouracil: NADP+ oxidoreductase, EC 1.3.1.2; DPD] enzyme was purified from the bovine ...
Imdat Aygul +2 more
doaj +1 more source
Our meta‐analysis aggregated existing results from relevant studies to comprehensively investigate the correlations between genetic polymorphisms in dihydropyrimidine dehydrogenase (DPYD) gene and 5‐fluorouracil (5‐FU) toxicities in patients with colorectal cancer (CRC).
Qiang Li +7 more
wiley +1 more source
A rare variant in DPYD c.812delT causes severe adverse events of S-1 in a patient with tongue cancer. [PDF]
Ishimura H +14 more
europepmc +1 more source
Impact of renal impairment on dihydropyrimidine dehydrogenase (DPD) phenotyping. [PDF]
Royer B +6 more
europepmc +1 more source
The Impact of Upfront DihydroPyrimidine Dehydrogenase (DPD) Testing on the Therapeutic Management of Patients Scheduled for 5-FU. [PDF]
Kallee G +5 more
europepmc +1 more source
Allelic Variants of the <i>DPYD</i> Gene in Russian Patients with Cancer: The Results of Exome Sequencing. [PDF]
Fedorinov D +10 more
europepmc +1 more source

