Results 81 to 90 of about 49,544 (290)

Mitochondrial Protection and Neural Repair via ROS‐Responsive Biomimetic Nanoparticles in Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
A ROS‐responsive biomimetic nanoparticle platform co‐delivers DIDS and Mdivi‐1 to protect mitochondria and promote neural repair after intracerebral hemorrhage. By targeting LPAR1/VDAC1‐related mitochondrial dysfunction, the nanotherapy reduces oxidative injury, neuronal apoptosis, and blood‐brain barrier disruption, improving neurological recovery and
Ling Gao   +7 more
wiley   +1 more source

DIY selves? [PDF]

open access: yesEuropean Journal of Cultural Studies, 2006
In Ulrich Beck's writings on the ‘risk society' he depicts contemporary western social identity as reflexive and ad hoc-shaped through calculative strategies of self-management rather than traditional social categories such as class. Beck's model of ‘reflexive individualization' can be seen to be particularly pertinent to the realm of health today ...
openaire   +4 more sources

EPBD 2023, F-GAS 2024, Eco-design and safety standards: Which design margins to be compliant with? An assessment of heat pumps for cooling [PDF]

open access: yesE3S Web of Conferences
To decarbonize Europe achieving almost zero emissions in 2050, more stringent regulations are going to be applied. Particularly, Europe is investing in the emissions’ re-duction of buildings (existing and new ones), and strong improvements in energy ...
Ascione Fabrizio   +5 more
doaj   +1 more source

Neuronal tracing with DiI: decalcification, cryosectioning, and photoconversion for light and electron microscopic analysis.

open access: yes, 1990
The molecule 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (DiI) is a fluorescent dye which diffuses within cell membranes. The properties of DiI diffusion and fluorescence are maintained in aldehyde-fixed tissue, thereby allowing ...
D E Cunningham   +2 more
core   +1 more source

Association between Maternal Dietary Inflammatory Index (DII) and Abortion in Iranian Women and Validation of DII with Serum Concentration of Inflammatory Factors: Case-Control Study [PDF]

open access: yes, 2016
Background: Previous studies have shown that some dietary components may be implicated in the etiology of abortion. However, the possible relationship between diet-related inflammation and the risk of abortion has not yet been investigated.
Vahid, Farhad   +5 more
core   +1 more source

3D Bioprinted Blood–Brain–Tumor Barrier Spheroid‐Based In Situ Evaluation of Anticancer Compounds Against Glioblastoma: ROS‐Producing Ruthenium as a Potential Therapeutic Candidate

open access: yesAdvanced Science, EarlyView.
The blood–brain–tumor barrier (BBTB) penetration by anticancer drugs and their effects on glioblastoma (GBM) is assessed using 3D bioprinted‐spheroids. Anticancer drug‐induced U‐87 MG cell death is quantified through in situ imaging of spheroids using a cancer cell death probe. The Ru compound, a partial P‐gp substrate, induces greater tumor‐cell death
Hyunjung Lee   +5 more
wiley   +1 more source

Association between dietary inflammation index and frailty among community medical staff

open access: yesFrontiers in Nutrition
ObjectiveTo investigate the relationship between the Dietary Inflammation Index (DII) and frailty among community medical staff.MethodsA stratified cluster sampling method was used to select community healthcare staff from Pudong New Area, Shanghai ...
Qinglian Lu   +8 more
doaj   +1 more source

Mitochondria‐Targeting Iron–Carbon Nanozymes Combat Hepatic Ischemia–Reperfusion Injury via the Dual Mechanisms of Respiratory Chain Remodeling and Pyroptosis Inhibition With MRI Monitoring

open access: yesAdvanced Science, EarlyView.
A mitochondrial‐targeted FeCD‐SS31 nanoplatform integrates ROS‐responsive SS31 release with cascade antioxidant Fe3O4/CDs cores to suppress both de novo and existing ROS. By restoring mitochondrial complex integrity and blocking caspase‐1–GSDMD‐N pyroptosis, it reduces neutrophil infiltration and alleviates hepatic ischemia–reperfusion injury, while ...
Qianying Du   +12 more
wiley   +1 more source

DII Softball Championships Central [PDF]

open access: yes, 2017
DII Softball Championships Central. The Armstrong State University softball squad is on its way to Salem, Va., for the 2017 NCAA Division II Softball Championships, hosted at the James I.
Armstrong State University
core  

Intratumoral Fusogenic Outer Membrane Vesicles Enhance Antitumor Immunity Through Tumor MHC‐I Upregulation and Tumor Bacterization

open access: yesAdvanced Science, EarlyView.
Tumor bacterization by fusogenic outer membrane vesicles enhances microbial‐like recognition of tumor cells while activating the TLR4–NF‐κB–NLRC5 axis to upregulate MHC class I expression. By simultaneously strengthening APC sensing and T‐cell recognition, this strategy breaks tumor immune invisibility and promotes more effective antitumor immune ...
Xing Liu   +9 more
wiley   +1 more source

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