Results 71 to 80 of about 15,788,610 (233)

The fishbone instability in the DIII-D tokamak [PDF]

Nuclear Fusion, 1990
Although most DIII-D plasmas are stable to the fishbone instability, fishbones are sometimes observed when βp 1.5 and e 5 × 1013 cm−3. These bursts are usually of minor significance operationally; however, under one condition, over 50% of the beam power was lost.
Heidbrink, WW, Sager, G
openaire   +3 more sources

Selective modulation of NaV channel gating counteracts aberrant hyperexcitability and rescues motor function and survival in a model of spinal muscular atrophy

British Journal of Pharmacology, EarlyView.
Background and Purpose Spinal muscular atrophy (SMA) is a motor neuron disease caused by SMN1 gene loss, leading to reduced survival motor neuron (SMN) protein and progressive motor neuron degeneration. Although SMN‐restoring therapies improve outcomes, residual disease burden and non‐curative efficacy underscore the need for complementary treatments ...
Fernanda C. Cardoso, Jessica A. I. Muller, Yougang Zhang, Jean Giacomotto   +3 more
wiley   +1 more source

Applications of ECH on the DIII-D tokamak and projections for future ECH upgrades

EPJ Web of Conferences, 2012
Electron Cyclotron Heating and Current Drive plays an important role in the DIII-D program. In high performance discharges EC power contributes greatly to MHD stability, and this is particularly important for discharges with low rotational torque applied,
Solomon W.M., Politzer P.A., Petty C.C., Luce T.C., Lohr J.M., La Haye R.J., Jackson G.L., Holcomb C.T., Garofalo A., Ferron J.R., DeBoo J., Buttery R.J., Prater R., Turco F.   +13 more
doaj   +1 more source

MHD stability of negative triangularity DIII-D plasmas

Nuclear Fusion, 2023
Negative triangularity (NT) experiments in DIII-D point to an emergent reactor scenario free of sawteeth, endowed with benign, nondisruptive n = 2 tearing modes, which experience q _min $ \geqslant $ 1 similar to the positive triangularity hybrid ...
W. Boyes, F. Turco, J. Hanson, A. Marinoni, A. Turnbull, M. Austin, G. Navratil   +6 more
doaj   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source

Bacillus thuringiensis Cry4Ba Insecticidal ToxinExploits Leu⁶¹⁵ in Its C-Terminal Domain to Interact with a Target Receptor—Aedes aegypti Membrane-Bound Alkaline Phosphatase

Toxins, 2021
In addition to the receptor-binding domain (DII), the C-terminal domain (DIII) of three-domain Cry insecticidal δ-endotoxins from Bacillus thuringiensis has been implicated in target insect specificity, yet its precise mechanistic role remains unclear ...
Anon Thammasittirong, Sutticha Na-Ranong Thammasittirong, Chompounoot Imtong, Sathapat Charoenjotivadhanakul, Somsri Sakdee, Hui-Chun Li, Siriporn Okonogi, Chanan Angsuthanasombat   +7 more
doaj   +1 more source

Optimized baking of the DIII-D vessel [PDF]

18th IEEE/NPSS Symposium on Fusion Engineering. Symposium Proceedings (Cat. No.99CH37050), 2003
The DIII-D tokamak vacuum vessel baking system is used to heat the vessel walls and internal hardware to an average temperature of 350/spl deg/C to allow rapid conditioning of the vacuum surfaces. The system combines inductive heating and a circulating hot air system to provide rapid heating with temperature uniformity required by stress considerations.
Anderson, P. M., Kellman, A. G.
openaire   +1 more source

Electrostatic tuning of NaV channel activation by the domain II S3–S4 extracellular loop

The Journal of Physiology, EarlyView.
Abstract figure legend Voltage‐gated sodium (NaV) channels are critical for electrical signalling, yet the molecular determinants that tune isoform‐specific activation remain incompletely understood. Here, we show that charged amino acids in the extracellular DII S3–S4 loop of NaV1.7 play a key role in setting voltage‐dependent activation.
Ashvriya Thapa, Lotten Ragnarsson, Hue Tran, Angelo Keramidas, Jennifer R. Deuis, Irina Vetter   +5 more
wiley   +1 more source

Experiments on plasma detachment in a V-shaped slot divertor in the DIII-D tokamak

Nuclear Fusion
Experiments in DIII-D demonstrate that the upstream plasma density to detach an un-pumped slot divertor is similar for a V-shaped and a flat-end slot, despite significantly higher neutral pressure in the V-shaped slot and in contrast to SOLPS-ITER ...
R. Maurizio, D. Thomas, J.H. Yu, T. Abrams, A.W. Hyatt, J. Herfindal, A. Leonard, X. Ma, A.G. McLean, J. Ren, F. Scotti, M.W. Shafer, G. Sinclair, H.Q. Wang, J. Watkins   +14 more
doaj   +1 more source

Characterization of wall conditions in DIII-D [PDF]

Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films, 1997
Wall conditioning in DIII-D is one of the most important factors in achieving reproducible high confinement discharges. For example, the very high confinement mode (VH-mode) was only discovered after boronization, a chemical vapor deposition technique to deposit a thin boron film over the entire surface of the tokamak.
Holtrop, K. L., Jackson, G. L., Kellman, A. G., Lee, R. L., West, W. P., Wood, R. D., Whyte, D. G.   +6 more
openaire   +1 more source