Immune-inflammatory concept of the pathogenesis of chronic heart failure in dogs with dilated cardiomyopathy [PDF]
Background: Dilated cardiomyopathy is common in dogs. This form of cardiomyopathy is the main cause of death due to heart disease in dogs. Death can occur suddenly in clinically normal animals as a result of the progression of congestive heart failure ...
Yu Vatnikov+9 more
doaj +2 more sources
Demographic and regional mortality trends in dilated cardiomyopathy in the United States; 1999–2020 [PDF]
Background: Dilated cardiomyopathy significantly impacts mortality and hospitalizations in the U.S., yet trends in dilated cardiomyopathy-related mortality are underreported.
Syed Sarmad Javaid+9 more
doaj +2 more sources
Layer-Specific Strain Analysis in Patients with Dilated Cardiomyopathy [PDF]
Background/Objectives: This study aimed to evaluate layer-specific strain according to etiology and assess whether subtle changes in longitudinal and circumferential layer strain are involved in predicting cardiac mortality during a two-year follow-up in
Despina-Manuela Toader+6 more
doaj +2 more sources
Dilated cardiomyopathy due to novel LMNA mutation: a case report [PDF]
A case of a 44-year-old man presenting with a family history of LMNA mutation and cardiac symptoms (dizziness, weakness, palpitations, and shortness of breath) congruent with dilated cardiomyopathy.
Riddhi Patel+3 more
doaj +2 more sources
Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy
Mutations in RNA binding motif protein 20 (RBM20) are a common cause of familial dilated cardiomyopathy (DCM). Many RBM20 mutations cluster within an arginine/serine-rich (RS-rich) domain, which mediates nuclear localization. These mutations induce RBM20
Takahiko Nishiyama+11 more
semanticscholar +1 more source
An Unusual Case of 11αB‐Crystallin (CRYAB) Mutation as a Cause of Dilated Cardiomyopathy With Restrictive Physiology: A Case Report and Focused Review of the Literature [PDF]
Several diseases have been linked to αB‐crystallin (CRYAB) mutation. However, this mutation is an uncommon cause that has been associated in recent years with the development of dilated cardiomyopathy.
Porras Bueno Cristian Orlando+5 more
doaj +2 more sources
A predictive model for canine dilated cardiomyopathy—a meta-analysis of Doberman Pinscher data [PDF]
Dilated cardiomyopathy is a prevalent and often fatal disease in humans and dogs. Indeed dilated cardiomyopathy is the third most common form of cardiac disease in humans, reported to affect approximately 36 individuals per 100,000 individuals.
Siobhan Simpson+5 more
doaj +2 more sources
Evidence-Based Assessment of Genes in Dilated Cardiomyopathy
Supplemental Digital Content is available in the text. Background: Each of the cardiomyopathies, classically categorized as hypertrophic cardiomyopathy, dilated cardiomyopathy (DCM), and arrhythmogenic right ventricular cardiomyopathy, has a signature ...
Elizabeth Jordan+33 more
semanticscholar +1 more source
Truncated titin proteins in dilated cardiomyopathy
Description Truncating mutations in TTN result in both truncated titin proteins and reduced full-length titin in patient hearts. Tracking titin in dilated cardiomyopathy Truncating variants in TTN, the gene encoding the titin protein, underlie 15 to 25 ...
Q. McAfee+14 more
semanticscholar +1 more source
To determine the prognostic value of multilevel assessment of fibrosis in dilated cardiomyopathy (DCM) patients.
A. Raafs+15 more
semanticscholar +1 more source