Results 231 to 240 of about 145,091 (327)

Tissue‐Specific Extraction and Structural Elucidation of Actin‐Tropomyosin‐Myosin Complexes from Human and Rodent

Aggregate, Volume 7, Issue 1, January 2026.
We developed a general tissue‐extraction strategy that directly purifies native F‐actin and actin–tropomyosin–myosin (ATM) complexes from human and rodent muscles for cryo‐EM. Near‐atomic structures, including an HCM R404Q mouse model, reveal how a disease myosin mutation remodels ATM assembly and alters myosin conformation at the actin interface ...
Danni Li, Qinyue Zhao, Youqi Tao, Shiran Lv, Wanbing Zhao, Yunxia Li, Xingyu Xiong, Zhizhi Wang, Wenqing Xu, Yaoyang Zhang, Cong Liu, Weidong Le, Wenyan Kang, Dan Li, Qin Cao, Bin Dai   +15 more
wiley   +1 more source

Time-dependent prognostic improvement by late gadolinium enhancement in dilated cardiomyopathy. [PDF]

J Cardiovasc Magn Reson
Tang S, Xu Y, Li Y, Li W, Guo J, Wan K, Wang J, Zhang Q, Han Y, Chen Y.   +9 more
europepmc   +1 more source

Advances and Applications of Spatial Proteomics: From Organellar Maps to Clinical Translation

ChemBioChem, Volume 27, Issue 1, January 2026.
Spatial proteomics provides high‐resolution maps of protein localization and trafficking by combining advanced mass spectrometry with complementary imaging and computational tools. Emerging low‐input and automated workflows are expanding its applicability to challenging clinical samples, supporting mechanistic disease research and biomarker discovery ...
Chiara Bernardini, Maike Däther, Franziska R. Traube   +2 more
wiley   +1 more source

New Biomarkers in the Diagnosis and Prognosis of Dilated Cardiomyopathy: Pro-Resolving Lipids and miRNAs. [PDF]

Cells
Jaén RI, Sánchez-García S, Fernández-Velasco M, Cuadrado I, de Las Heras B, Boscá L, Prieto P.   +6 more
europepmc   +1 more source

Multi‐Chamber Intracardiac Thrombi Complicated With Pulmonary and Lower Extremity Thrombosis in Male Patient: Case Report and Literature Reviews

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Multi‐chamber intracardiac thrombi are a rare and high‐risk complication in dilated cardiomyopathy, even during sinus rhythm. This case highlights the associated dangers of hemodynamic compromise and systemic embolization. Management requires vigilant anticoagulation and close monitoring to balance thromboembolic and bleeding risks.
Eba Fufa, Yitagesu Getachew, Samson Mulugeta, Abera Birhanu, Abel Yirga, Amdemeskel Mersha, Banchiaymolu Damtie, Balew Arega, Begashaw Belay, Brook Fanuel, Misgana Lukas   +10 more
wiley   +1 more source

Atrioventricular Delay Optimization in His‐Optimized Cardiac Resynchronization Therapy: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT His bundle pacing (HBP) has recently emerged as a physiologic pacing strategy that preserves ventricular synchrony and may improve outcomes in patients with heart failure and conduction abnormalities. Optimization of the atrioventricular (AV) delay plays a pivotal role in ensuring hemodynamic efficiency in patients with conduction system ...
Minh Nguyen Quang, Dung Kieu Ngoc, Son Nguyen Khac Le, Phuong Tran Le Uyen, Thuc Nguyen Tri   +4 more
wiley   +1 more source

Implication of intracellular chloride channel in extracellular matrix remodeling in pressure-overloaded mice and patients with dilated cardiomyopathy. [PDF]

Physiol Rep
Oguri G, Nomura S, Nakajima T, Kikuchi H, Obi S, Komuro I, Takeda N, Toyoda S, Nakajima T.   +8 more
europepmc   +1 more source

Early Onset Heart Failure due to RBM20 Variant: A Case Report Emphasizing Genetic Diagnosis and Arrhythmic Risk Stratification

Clinical Case Reports, Volume 14, Issue 1, January 2026.
Transthoracic echocardiography demonstrating biventricular dilatation. Parasternal long‐ and short‐axis views and apical four‐ and two‐chamber views show marked left ventricular dilatation with increased end‐diastolic volume, associated with right ventricular dilatation.
Cristian Orlando Porras Bueno, Cesar Augusto Balaguera, Alejandro Mariño Correa, Edward Andrés Cáceres Méndez   +3 more
wiley   +1 more source

Titin-related familial dilated cardiomyopathy: factors associated with disease onset. [PDF]

Eur Heart J
Johnson R, Fletcher RA, Peters S, Ohanian M, Soka M, Smolnikov A, Abihider KE, Ackerman MJ, Ader F, Akhtar MM, Amin AS, Ashley EA, Atherton JJ, Austin R, Baas AF, Bagnall RD, Ross SB, Blouin JL, Brown EE, Bundgaard H, Cannie D, Chmielewski P, Correnti G, Crespo-Leiro MG, Dal Ferro M, Dellefave-Castillo LM, Dominguez F, Dooijes D, Dybro AM, Ed Demri Y, El Hachmi M, Escobar-Lopez L, Foye SJ, Franaszczyk M, Gigli M, Lopez EG, Goudal A, Graw S, Guipponi M, Haan E, Haas J, Hammersley DJ, Hansen FG, Hayward CS, Hey TM, Heymans S, Ho CY, Houweling AC, Ingles J, Ingrey A, Jabbour A, James PA, Jansweijer JA, Jongbloed JDH, Keogh AM, Larrañaga-Moreira JM, Lekanne Deprez RH, Macciocca I, Macdonald PS, Mansencal N, Mansour J, Martinez-Veira C, McDonough B, McGaughran J, Medo K, Merlo M, Michalak E, Monserrat L, Mountain H, Muller SA, Murphy AM, Murray B, Oates EC, Ormondroyd E, Pachter N, Paldino A, Palmyre A, Pereira NL, Picard KC, Poplawski N, Prasad S, Proukhnitzky J, Pruny JF, Reant P, Richard P, Ronan A, Sedaghat-Hamedani F, Semsarian C, Storm G, Stroeks S, Syrris P, Taylor MRG, Thomson K, Thompson T, van Tintelen JP, Vissing CR, Waddell-Smith KE, Wallis M, Zentner D, Australian Genomics Cardiac Flagship, Arnott C, Marian AJ, Oh J, Fokstuen S, James CA, Barriales-Villa R, Meder B, Wahbi K, Giudicessi JR, Parikh VN, Ware JS, Piriou N, Rooryck C, Lakdawala NK, Mestroni L, Sinagra G, Elliott PM, Watkins H, McNally EM, Charron P, van Spaendonck-Zwarts KY, Garcia-Pavia P, Peña-Peña ML, Mogensen J, Christensen AH, Bilińska ZT, Rasmussen TB, Seidman JG, Seidman CE, Te Riele ASJM, Verdonschot JAJ, Pinto YM, Christiaans I, Fatkin D.   +133 more
europepmc   +1 more source

Changes of Serum CTRP12 in Patients With Coronary Artery Disease After the Treatment of Percutaneous Coronary Intervention and Its Relationship With In‐Stent Restenosis

Clinical Cardiology, Volume 49, Issue 1, January 2026.
Serum CTRP12 levels are significantly lower in CAD patients, and significant correlate to disease severity and dynamic changes after PCI. They may serve as a potential biomarker for diagnosing CAD and predicting ISR occurrence. ABSTRACT Background C1q/tumor necrosis factor‐related protein 12 (CTRP12) plays a protective role in coronary artery disease ...
Botao Zhao, Yuchao Shen
wiley   +1 more source