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Mitochondrial Function and Dysfunction in Dilated Cardiomyopathy
Frontiers in Cell and Developmental Biology, 2021 Cardiac tissue requires a persistent production of energy in order to exert its pumping function. Therefore, the maintenance of this function relies on mitochondria that represent the “powerhouse” of all cardiac activities.
D. Ramaccini +10 more
semanticscholar +1 more source
Familial Dilated Cardiomyopathy [PDF]
Heart, Lung and Circulation, 1992 Advances in human genome sequencing have re-invigorated genetics studies of dilated cardiomyopathy (DCM), facilitating genetic testing and clinical applications. With a range of genetic testing options now available, new challenges arise for data interpretation and identifying single pathogenic variants from the many thousands of rare variants present ...
Steven S. Coughlin, Raymond L. Woosley
+9 more sources
An Evidence-based Assessment of Genes in Dilated Cardiomyopathy
medRxiv, 2020 Background: The cardiomyopathies are classically categorized as hypertrophic (HCM), dilated (DCM), and arrhythmogenic right ventricular (ARVC), and each have a signature genetic theme.
Elizabeth Jordan +33 more
semanticscholar +1 more source
Protein & Cell, 2020 Dysregulation of circadian rhythms associates with cardiovascular disorders. It is known that deletion of the core circadian gene Bmal1 in mice causes dilated cardiomyopathy.
Ermin Li +9 more
semanticscholar +1 more source
The Effect of Type 2 Diabetes Mellitus on the Prognosis of Patients with Dilated Cardiomyopathy [PDF]
Zhongguo quanke yixue, 2023 Background Type 2 diabetes mellitus increases the risk of early onset of cardiovascular disease in patients, which poses a major threat to human health. Exploring the impact of type 2 diabetes mellitus on prognosis of patients with dilated cardiomyopathy
WANG Haiyan, HUANG Yuan, GUI Chun
doaj +1 more source
Dilated cardiomyopathy and aldosteronoma: a causal link?
ESC Heart Failure, 2020 The aim of this study is to reveal the causal relationship between dilated cardiomyopathy and aldosteronoma. A 44‐year‐old male dilated cardiomyopathy patient with aldosteronoma, who demonstrated a worse cardiac function after 1 year therapy with ...
Jiyu Zhang, Jin Yang, Yueliang Li
doaj +1 more source
Implications of Genetic Testing in Dilated Cardiomyopathy
Circulation Genomic and Precision Medicine, 2020 Supplemental Digital Content is available in the text. Background: Genetic analysis is a first-tier test in dilated cardiomyopathy (DCM). Electrical phenotypes are common in genetic DCM, but their exact contribution to the clinical course and outcome is ...
J. Verdonschot +11 more
semanticscholar +1 more source
An upgrade on the rabbit model of anthracycline-induced cardiomyopathy: shorter protocol, reduced mortality, and higher incidence of overt dilated cardiomyopathy [PDF]
, 2015 Current protocols of anthracycline-induced cardiomyopathy in rabbits present with high premature mortality and nephrotoxicity, thus rendering them unsuitable for studies requiring long-term functional evaluation of myocardial function (e.g., stem cell ...
Brooks, Gavin +6 more
core +8 more sources
Circulation Cardiovascular Imaging, 2020 Supplemental Digital Content is available in the text. Background: Dilated cardiomyopathy is associated with increased risk of major cardiovascular events.
A. Alba +22 more
semanticscholar +1 more source
Familial dilated cardiomyopathy [PDF]
Heart, 1994 ardiomyopathies are diseasesof the heart muscle that renderthe heart unable to properlypump enough blood to the body. In thedilated form of cardiomyopathy(called dilated cardiomyopathy orDCM), the heart is enlarged (Figure 1).As the heart enlarges, it becomes lesseffective in pumping blood, whichthen leads to symptoms of heart failureand irregular ...
L. Mestroni +7 more
openaire +4 more sources