Results 71 to 80 of about 580,532 (393)

Reversal of Stress‐Induced PIEZO1 Elevation with Mechanically Adapted Epicardial Patch for Myocardial Infarction Treatment

Advanced Science, EarlyView.
This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu, Sibo Jiang, Ting Shen, Yuan Zhang, Chengbin He, Yun Gao, Liyin Shen, Qiao Jin, Yuting Zhao, Ping Liang, Chaochen Wang, Hongjie Hu, Jin He, Kaicheng Deng, Shuo Wang, Yunhe Chen, Jun Ling, Yang Zhu, Lenan Zhuang   +18 more
wiley   +1 more source

Prevalence of hepatitis C and B virus infection in patients with idiopathic dilated cardiomyopathy in Brazil: a pilot study

Brazilian Journal of Infectious Diseases
The idiopathic dilated cardiomyopathy (IDMC) is a disease of the cardiac muscle characterized by systolic dilation and/or dysfunction of one or both ventricles, symptoms of congestive heart failure and risk of early death.
Francisco J.F.B. Reis, Mateus Viana, Manoela Oliveira, Tiago A. Sousa, Raimundo Paraná   +4 more
doaj   +1 more source

Inter- Not Intraindividual Differences in sTWEAK Levels Predict Functional Deterioration and Mortality in Patients with Dilated Cardiomyopathy

Mediators of Inflammation, 2014
Background. TNF-like weak inducer of apoptosis (TWEAK) has been reported to predict mortality in patients with dilated cardiomyopathy. However, whether it can be used as a biomarker for disease monitoring or rather represents a risk factor for disease ...
Kai-Uwe Jarr, Manfred Nelles, Hugo A. Katus, Emmanuel Chorianopoulos   +3 more
doaj   +1 more source

Dilated cardiomyopathy: from epidemiologic to genetic phenotypes

Journal of Internal Medicine, 2019
Dilated cardiomyopathy (DCM) is characterized by left ventricular dilatation and, consecutively, contractile dysfunction. The causes of DCM are heterogeneous. DCM often results from myocarditis, exposure to alcohol, drugs or other toxins and metabolic or
Daniel Reichart, C. Magnussen, T. Zeller, S. Blankenberg   +3 more
semanticscholar   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models

Advanced Science, EarlyView.
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang, Fang Li, Jiao Liu, Shu‐Ang Li, Dan‐Hua Liu, Zhuanbin Wu, Pei‐Pei Liu, Wenju Liu, Bin Zhou, Cizhong Jiang, Haibing Zhang, Ying Yu, Jian‐Sheng Kang   +12 more
wiley   +1 more source

Research Progress and Forensic Identification of Alcoholic Cardiomyopathy [PDF]

Fayixue Zazhi, 2019
With the rapid development of the social economy in China, the incidence of diseases caused by excessive drinking is gradually increasing as well. Alcoholic cardiomyopathy refers to long-term high intake of ethanol, and has typical dilated cardiomyopathy
ZHANG Tian-yi, GAO Wei-min, CAO Zhi-peng,et al.
doaj   +1 more source

Determinants of minute ventilation-carbon dioxide production relationship in Chagas cardiomyopathy

Revista da Sociedade Brasileira de Medicina Tropical, 2021
INTRODUCTION: The minute ventilation-carbon dioxide production relationship (VE/VCO2 slope) is among the main prognostic factors of Chagas cardiomyopathy whose determinants remain unknown. METHODS: Seventy-eight patients with Chagas cardiomyopathy were
Lucas Frois Fernandes Oliveira, Janaina Martins Andrade, Pedro Henrique Scheidt Figueiredo, Matheus Ribeiro Ávila, Whesley Tanor Silva, Marcus Vinicius Accetta Vianna, Renato Guilherme Trede Filho, Henrique Silveira Costa, Manoel Otávio Costa Rocha, Vanessa Pereira Lima   +9 more
doaj   +1 more source

Short-term Heart Rate Turbulence Analysis Versus Variability and Baroreceptor Sensitivity in Patients With Dilated Cardiomyopathy [PDF]

, 2004
New methods for the analysis of arrhythmias and their hemodynamic consequences have been applied in risk stratification, in particular to patients after myocardial infarction.
Bauernschmitt, Robert, Malberg, Hagen, Meyerfeldt, Udo, Schirdewan, Alexander, Wessel, Niels   +4 more
core   +1 more source

Acute echocardiographic effects of sotalol on ventricular systolic function in dogs with ventricular arrhythmias. [PDF]

, 2018
BackgroundSotalol is a commonly used antiarrhythmic drug that may alter ventricular function.ObjectiveTo determine the effect of sotalol on echocardiographic indices of ventricular systolic function in dogs with ventricular arrhythmias.AnimalsThirty-five
Anderson, Baumwart, Chetboul, Cornell, Dukes-McEwan, Hansson, Hoffmann, Hohnloser, Kaye, Mahmarian, Maran, Martin, Meurs, Meurs, Meurs, Meurs, Motskula, Oyama, Palermo, Peralta, Schnelle, Seidler, Singh, Smets, Stephenson, Summerfield, Visser, Visser, Wess, Wess, Zupan   +30 more
core   +2 more sources