Results 101 to 110 of about 226,843 (240)
Advanced Science, EarlyView.Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka +3 more
wiley +1 more source
Medicina Veterinária, 2020 Megaesophagus is a disease characterized by generalized esophageal dilatation, resulting from reduced or absent esophageal motility. It can be congenital or acquired and some common causes are persistent right aortic arch and myasthenia gravis.
Juliana Roberts Oaskis +6 more
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G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Communications, 2012 The quarry of Mokra, whose locality comprises administrative area of three communities, has cooperated with our Institute for a longer time, communicating with the authorities and people, as regards environmental safety and quality of living in the area.
Milan Mikolas +4 more
doaj +1 more source
Isometric Dilations of Representations of Product Systems via Commutants
, 2006 We construct a weak dilation of a not necessarily unital CP-semigroup to an E-semigroup acting on the adjointable operators of a Hilbert module with a unit vector.
Michael Skeide, Via Commutants
core +1 more source
Advanced Science, EarlyView.High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani +10 more
wiley +1 more source
Advanced Science, EarlyView.Endothelial GPR68 is identified as a critical regulator of collateral artery growth in peripheral artery disease. Genetic and pharmacological evidence demonstrates that GPR68 integrates hemodynamic cues to drive monocyte recruitment and inflammatory remodeling, thereby promoting collateral arteriogenesis and tissue perfusion after ischemia ...
Yiyan Song +12 more
wiley +1 more source
Advanced Science, EarlyView.A neutrophil‐mediated dual‐targeting liposome (NKN‐LNP) is developed to treat renal ischemia–reperfusion injury. The system enables spatiotemporally controlled delivery of NMN to injured tubules via MMP‐2/9 activation and KIM1 recognition, restoring mitochondrial function through NAD+‐SIRT3 signaling and preventing the transition from acute kidney ...
Hangbin Ma +15 more
wiley +1 more source
Managing eosinophilic esophagitis: challenges and solutions
Clinical and Experimental Gastroenterology, 2016 Nisha A Shah, Dustin M Albert, Noah M Hall, Fouad J Moawad Department of Medicine, Gastroenterology Service, Walter Reed National Military Medical Center, Bethesda, MD, USA Abstract: Eosinophilic esophagitis (EoE) is a chronic and ...
Shah NA, Albert DM, Hall NM, Moawad FJ
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