Results 1 to 10 of about 833 (148)
Biodegradable microparticulate drug delivery system of diltiazem HCl [PDF]
The efficacy of a drug in a specific application requires the maintenance of appropriate drug blood level concentration during a prolonged period of time.
Manish Kumar Gupta +2 more
doaj +8 more sources
Diltiazem-loaded Eudragit RS 100 microparticles for drug delivery: the challenge of viscosity [PDF]
Strongly shape-dependent viscosity has been found in drug loaded and `empty` polymeric microspheres (drug delivery systems) made of pharmacopoeial Eudragit RS 100 representative.
Alexieva, Gergana E +4 more
core +3 more sources
OPTIMIZATION OF DILTIAZEM HYDROCHLORIDE NANOPARTICLES FORMULA AND ITS RELEASE KINETICS EVALUATION [PDF]
Objective: The purpose of this study was to determine the optimum formula of diltiazem HCl-loaded chitosan nanoparticles due to variations in the speed and duration of stirring and evaluating the release kinetics in vitro using DDSolver.
AMELIANA, LIDYA +6 more
core +3 more sources
Locust bean gum: Exploring its potential for biopharmaceutical applications. [PDF]
Polysaccharides have been finding, in the last decades, very interesting and useful applications in the biomedical and, specifically, in the biopharmaceutical field.
Dionísio M, Grenha A.
europepmc +3 more sources
Sulfated Seaweed Polysaccharides as Multifunctional Materials in Drug Delivery Applications. [PDF]
In the last decades, the discovery of metabolites from marine resources showing biological activity has increased significantly. Among marine resources, seaweed is a valuable source of structurally diverse bioactive compounds.
Cunha L, Grenha A.
europepmc +4 more sources
Ropinirole HCl is a non-ergoline dopamine agonist which is recommended for the treatment of both Parkinson’s disease and Restless Legs Syndrome (RLS). Its half-life is about 6 hours and it is metabolized in the liver primarily by CYP1A2.
Nabeel Siddique
semanticscholar +1 more source
Vancomycin hydrochloride (HCl) is a glycopeptide antibiotic used to treat serious or life-threatening infections, and it reduces plaque scores and gingivitis in periodontal patients.
Tiraniti Chuenbarn +4 more
semanticscholar +1 more source
Oral pioglitazone HCl-loaded solid lipid microparticles: Formulation design and bioactivity studies
Pioglitazone hydrochloride (PGZ) is a hypoglycemic drug used to treat type 2 diabetes with a short biological half-life and poor oral absorption. The current study was conducted to prepare oral PGZ-loaded lipid microparticles (PGZ-LMPs) for improving PGZ’
M. Rafiee +3 more
semanticscholar +1 more source
In vivo Assessment of Diltiazem HCl Immobilized Co-polymeric pH Sensitive Microgels
Novel stimuli responsive coplymeric (2-ethyl hexyl acrylate -co- itaconic acid diltiazem HCl loaded microgels were fabricated and characterized successfully to reduce the degradation of drugs in acidic pH of stomach resulting in reduced bioavailability ...
Rabia Razzaq +3 more
semanticscholar +1 more source
The aim of this study was to improve the solubility of etoposide–ethylcellulose (ET–ETO) microparticles using the freeze-drying technique. Ethylcellulose (EC) microparticles loaded with etoposide (ETO) were prepared with different drug–polymer molar ...
A. Abdellatif +7 more
semanticscholar +1 more source

