Results 1 to 10 of about 833 (148)

Biodegradable microparticulate drug delivery system of diltiazem HCl [PDF]

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2012
The efficacy of a drug in a specific application requires the maintenance of appropriate drug blood level concentration during a prolonged period of time.
Manish Kumar Gupta   +2 more
doaj   +8 more sources

Diltiazem-loaded Eudragit RS 100 microparticles for drug delivery: the challenge of viscosity [PDF]

open access: yesScripta Scientifica Pharmaceutica, 2018
Strongly shape-dependent viscosity has been found in drug loaded and `empty` polymeric microspheres (drug delivery systems) made of pharmacopoeial Eudragit RS 100 representative.
Alexieva, Gergana E   +4 more
core   +3 more sources

OPTIMIZATION OF DILTIAZEM HYDROCHLORIDE NANOPARTICLES FORMULA AND ITS RELEASE KINETICS EVALUATION [PDF]

open access: yesInternational Journal of Applied Pharmaceutics, 2021
Objective: The purpose of this study was to determine the optimum formula of diltiazem HCl-loaded chitosan nanoparticles due to variations in the speed and duration of stirring and evaluating the release kinetics in vitro using DDSolver.
AMELIANA, LIDYA   +6 more
core   +3 more sources

Locust bean gum: Exploring its potential for biopharmaceutical applications. [PDF]

open access: yesJ Pharm Bioallied Sci, 2012
Polysaccharides have been finding, in the last decades, very interesting and useful applications in the biomedical and, specifically, in the biopharmaceutical field.
Dionísio M, Grenha A.
europepmc   +3 more sources

Sulfated Seaweed Polysaccharides as Multifunctional Materials in Drug Delivery Applications. [PDF]

open access: yesMar Drugs, 2016
In the last decades, the discovery of metabolites from marine resources showing biological activity has increased significantly. Among marine resources, seaweed is a valuable source of structurally diverse bioactive compounds.
Cunha L, Grenha A.
europepmc   +4 more sources

Individual and Combined Effect of Eudragit® RS 100 and Eudragit® RL 100 on Sustained Release Characteristics of Ropinirole HCl-loaded Microparticles

open access: yesPharmaceutical Sciences and Research, 2023
Ropinirole HCl is a non-ergoline dopamine agonist which is recommended for the treatment of both Parkinson’s disease and Restless Legs Syndrome (RLS). Its half-life is about 6 hours and it is metabolized in the liver primarily by CYP1A2.
Nabeel Siddique
semanticscholar   +1 more source

Design and Comparative Evaluation of Vancomycin HCl-Loaded Rosin-Based In Situ Forming Gel and Microparticles

open access: yesGels, 2022
Vancomycin hydrochloride (HCl) is a glycopeptide antibiotic used to treat serious or life-threatening infections, and it reduces plaque scores and gingivitis in periodontal patients.
Tiraniti Chuenbarn   +4 more
semanticscholar   +1 more source

Oral pioglitazone HCl-loaded solid lipid microparticles: Formulation design and bioactivity studies

open access: yesJournal of Applied Pharmaceutical Sciences, 2022
Pioglitazone hydrochloride (PGZ) is a hypoglycemic drug used to treat type 2 diabetes with a short biological half-life and poor oral absorption. The current study was conducted to prepare oral PGZ-loaded lipid microparticles (PGZ-LMPs) for improving PGZ’
M. Rafiee   +3 more
semanticscholar   +1 more source

In vivo Assessment of Diltiazem HCl Immobilized Co-polymeric pH Sensitive Microgels

open access: yesFRONTIERS IN CHEMICAL SCIENCES, 2023
Novel stimuli responsive coplymeric (2-ethyl hexyl acrylate -co- itaconic acid diltiazem HCl loaded microgels were fabricated and characterized successfully to reduce the degradation of drugs in acidic pH of stomach resulting in reduced bioavailability ...
Rabia Razzaq   +3 more
semanticscholar   +1 more source

Freeze-Drying Ethylcellulose Microparticles Loaded with Etoposide for In Vitro Fast Dissolution and In Vitro Cytotoxicity against Cancer Cell Types, MCF-7 and Caco-2

open access: yesApplied Sciences, 2021
The aim of this study was to improve the solubility of etoposide–ethylcellulose (ET–ETO) microparticles using the freeze-drying technique. Ethylcellulose (EC) microparticles loaded with etoposide (ETO) were prepared with different drug–polymer molar ...
A. Abdellatif   +7 more
semanticscholar   +1 more source

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