Results 21 to 30 of about 833 (148)

Optimization and Characterization of Fenugreek Seed Polymer Nanoparticles Loaded with Diltiazem HCl Nanoparticles by Desolvation Method

open access: yesJournal of Drug Delivery and Therapeutics, 2019
The main aim of the present investigation is to optimize and evaluate the fenugreek seed polymer nanoparticles using Diltiazem HCl as a model drug because Diltiazem HCl has short half-life.
M. Ramya, Rajesh Akki, C. Jyothsna
semanticscholar   +1 more source

Controlled release floating multiparticulates of metoprolol succinate by hot melt extrusion [PDF]

open access: yes, 2015
YesWe present hot melt extrusion (HME) for the design of floating multiparticulates. Metoprolol succinate was selected as the model drug. Our foremost objective was to optimize the components Eudragit® RS PO, polyethylene oxide (PEO) and hydroxypropyl ...
Devarajan, P.V.   +2 more
core   +1 more source

Formulation, Optimization and Characterization of Chitosan Monodisperse Microparticles for Sustained Delivery of Hydrochlorothiazide HCl

open access: yesPharmaceutical Sciences, 2020
Background: Hydrochlorothiazide HCl (HCTZ) is first line medication in the management of hypertension, however its poor solubility and GI irritation warrants long term application.
Jahanzeb Mudassir   +5 more
semanticscholar   +1 more source

Study on the Development of Diltiazem HCl Loaded Colonic Drug Delivery Systems (CDDS) Using Various Polymers and Characterization of their Release Profiles by In Vitro Dissolution Studies

open access: yes, 2011
This investigation describes the preparation and in vitro evaluation of Colonic Drug Delivery of Diltiazem HCl tablet. Methocel K 4M premium, Methocel K 100M premium CR, Methocel K 15M CR and Xanthan gum were used for release controlling properties.
Muhammad Shahidul Islam   +2 more
semanticscholar   +1 more source

OVERVIEW ON FLOATING DRUG DELIVERY SYSTEM [PDF]

open access: yes, 2018
The principal objective behind the writing of this article on the floating drug delivery system (FDDS) was to systematize the recent literature with the core process of floatation in acquiring gastric retention.
Akkala, Madhukar   +2 more
core   +3 more sources

DESIGN AND IN VITRO EVALUATION OF FLOATING DRUG DELIVERY SYSTEM OF GLIPIZIDE USING COMBINATION OF NATURAL MUCILAGES AND SYNTHETIC POLYMERS [PDF]

open access: yes, 2021
Objective: The objective of the study is to explore polysaccharide mucilages of Colocasia esculenta (CE), and Fenugreek (FG) as buoyancy enhancing agents, and mucoadhesive agents by developing gastroretentive floating tablets of Glipizide.
CHOUDHARY, SURAJ KUMAR   +1 more
core   +1 more source

Inhalable Spray-Dried Chondroitin Sulphate Microparticles: Effect of Different Solvents on Particle Properties and Drug Activity

open access: yesPolymers, 2020
Spray-drying stands as one of the most used techniques to produce inhalable microparticles, but several parameters from both the process and the used materials affect the properties of the resulting microparticles.
Susana Rodrigues   +6 more
semanticscholar   +1 more source

EXPLORING THE POTENTIAL OF EUDRAGIT FOR DEVELOPMENT OF MICROPARTICLES OF WATER SOLUBLE DRUG USING QUALITY BY DESIGN APPROACH [PDF]

open access: yes, 2019
Objective: In the present protocol, employability of polymethacrylate polymer Eudragit RS100 for development of microparticles of water soluble drug with desired values of response variables was investigated by central composite optimization design ...
SETH, NIMRATA, SHARMA, SHAILESH
core   +3 more sources

FLOATING RANITIDINE MICROPARTICULATES: DEVELOPMENT AND IN VITRO EVALUATION [PDF]

open access: yes, 2016
Objective: Rapid and inconsistent gastrointestinal tract (GIT) transit could result in reduced drug efficiency and the need for frequent dose administration, which usually result in patients' incompliance.
Etman, Mohamed E.   +3 more
core   +2 more sources

Some Characteristics And Allopurinol Release Of Carrageenan/ Allopurinol Films Using Polyethylene Oxide As A Dispersion Aid Agent [PDF]

open access: yes, 2020
This paper presents the effect of carrageenan (CG) on some characteristics and drug release of allopurinol in the presence of polyethylene oxide (PEO) as a dispersion aid agent.
Nguyen, Chinh Thuy   +4 more
core   +2 more sources

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