Results 111 to 120 of about 1,866,979 (302)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Influence of quenched dilution on the quasi-long-range ordered phase of the 2d XY model

, 2003
The influence of non magnetic impurities in the 2d XY model is investigated through Monte Carlo (MC) simulations. The general picture of the transition is fully understood from the Harris criterion which predicts that the universality class is unchanged,
Berche, B., Holovatch, Yu., Paredes, R., Sanchez, A. I. Farinas   +3 more
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

DED Powder Modification for Single-Layer Coatings on High-Strength Steels

Journal of Manufacturing and Materials Processing
In the design of L-DED (laser-directed energy deposition) cladding processes, the chemical composition of the metallic powders is typically assumed to match that of the intended coating.
Unai Garate, Enara Mardaras, Jon Arruabarrena, Garikoitz Artola, Aitzol Lamikiz, Luis Norberto López de Lacalle   +5 more
doaj   +1 more source

Hydrocarbon ratios during PEM-WEST A: A model perspective [PDF]

, 1996
A useful application of the hydrocarbon measurements collected during the Pacific Exploratory Mission (PEM-West A) is as markers or indices of atmospheric processing. Traditionally, ratios of particular hydrocarbons have been interpreted as photochemical
Blake, DR, Bradshaw, JD, Gregory, GL, Hsie, EY, Lin, X, Liu, SC, McKeen, SA, Smyth, S   +7 more
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Statement to Water Resources Subcommittee of House Committee on Public Works and Transportation for a Hearing, May 24 and 25, 1978, Washington, D.C. regarding Secondary Treatment Waivers and Ocean Outfalls [PDF]

, 1978
The principal technical reason for having a waiver provision for secondary treatment for municipal discharges is that for some outfall systems the dilution is so high that very good ambient water quality can be achieved with less than secondary ...
Brooks, Norman H.
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

PHYSICAL, CHEMICAL AND SENSORY PROPERTIES OF KENARI (Canariun indicum L.) SHELL LIQUID SMOKE-IMMERSED-BEEF ON DIFFERENT LEVEL OF DILUTION [PDF]

Journal of the Indonesian Tropical Animal Agriculture, 2012
This research was aimed to study the effect of the dilution level of kenari shell liquid smoke to the physical, chemical and sensory properties of beef.
Yusnaini, Soeparno, E. Suryanto, R. Armunanto   +3 more
doaj  

Evaluation of antibacterial activity of hand sanitizers – an in vitro study

Journal of Applied Sciences and Environmental Management, 2018
Hand hygiene, particularly hand sanitizing, is essential in reducing infectious disease transmission. The recent outbreak of Ebola in Nigeria both increased public awareness of the practice of hand sanitizing and resulted in the introduction of new ...
K Otokunefor, I Princewill
doaj   +1 more source