Results 141 to 150 of about 2,144,368 (379)
Non-Linear Creatinine Dilution Adjustment of Exemplary Urine Arsenic - Part I: Curving the Lines
Thomas Clemens Carmine
openalex +1 more source
Classical percolation transition in the diluted two-dimensional S=1/2 Heisenberg antiferromagnet
The two-dimensional antiferromagnetic S=1/2 Heisenberg model with random site dilution is studied using quantum Monte Carlo simulations. Ground state properties of the largest connected cluster on L*L lattices, with L up to 64, are calculated at the ...
Sandvik, Anders W.
core +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Analysis of pristanic acid β-oxidation intermediates in plasma from healthy controls and patients affected with peroxisomal disorders by stable isotope dilution gas chromatography mass spectrometry [PDF]
Nanda M. Verhoeven +6 more
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Coccidioidomycosis Complement Fixation Titer Trends in the Age of Antifungals. [PDF]
Coccidioidomycosis is associated with a broad spectrum of illness severity, ranging from asymptomatic or self-limited pulmonary infection to life-threatening manifestations of disseminated disease.
Bays, Derek +6 more
core
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Dilution jet mixing program, phase 3 [PDF]
The objectives of the program were: (1) to extend the data base on mixing of a single-sided row of jets with a confined crossflow, (2) to collect a data base on mixing of multiple rows of jets with confined crossflow, (3) to develop empirical jet mixing ...
Myers, G., Srinivasan, R., White, C.
core +4 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

