Results 171 to 180 of about 2,092,591 (384)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Siblings and human capital: A comparison between Italy and France [PDF]

open access: yes
This paper investigates how family size affects children’s human capital, comparing Italy and France. We tested the dilution effect in these countries, starting with the assumption that the higher the number of siblings, the fewer parental resources are ...
Gianpiero Dalla Zuanna, Giulia Ferrari
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Perspectives on dilution jet mixing [PDF]

open access: yes
A microcomputer code which displays 3-D oblique and 2-D plots of the temperature distribution downstream of jets mixing with a confined crossflow has been used to investigate the effects of varying the several independent flow and geometric parameters on
Holdeman, J. D.
core   +1 more source

Inference, Not Dilution in the Dilution Effect

open access: yes, 2015
When asked to combine two pieces of evidence, one diagnostic and one non-diagnostic, people show a dilution effect: the addition of non-diagnostic evidence dilutes the overall strength of the evidence. This non-normative effect has been found in a variety of tasks and has been taken as evidence that people inappropriately combine information.
Sanborn, Adam   +3 more
openaire   +1 more source

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