Results 211 to 220 of about 1,866,979 (302)

A probiotic bacterium modulates antitumour γδ T-cell responses in lung cancer. [PDF]

Front Immunol
Goto Y, Dolton G, Thomas H, Morin T, Tajima Y, Imamura K, Sakata S, Oka K, Hayashi A, Takahashi M, Ueno T, Sakagami T, Tomita Y, Sewell AK, Motozono C.   +14 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

La³⁺ Networks and Speciation in the Molten State: Impact of Spacer Salt Selection on Structural Heterogeneity. [PDF]

J Am Chem Soc
Borah B, Emerson MS, Roy S, Ferrari JJ, Chapman KW, Gallington LC, Dhakal D, Kim EM, Halstenberg PW, Dai S, Gill SK, Wishart JF, Margulis CJ.   +12 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Protocol to annotate dendritic cell maturation types in vivo making use of lipid nanoparticle-based approaches. [PDF]

STAR Protoc
Van Lil K, Swinnen J, Webb GR, Rennen S, Bosteels V, Maréchal S, De Nolf C, Vetters J, Březina J, Van De Velde E, Fayazpour F, Verbeke R, Lentacker I, Janssens S.   +13 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Microecological insight into the microbial structure, key cellulolytic community, and microbial interaction during cellulose degradation in high-diversity and low-diversity communities. [PDF]

Appl Environ Microbiol
Zhang X, Xian A, Zhang X, Yang D, Zhang J, Chen G, Xing Z, Kang J, Lang K, Bao J, Li H, Ma B.   +11 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source