Results 21 to 30 of about 1,878,038 (247)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Análisis de los estándares de calidad y su incidencia en el desempeño docente de la Educación General Básica y Bachillerato de la Unidad Educativa Catalina Cadena del Cantón El Triunfo

open access: yesRevista Científica Ciencia y Tecnología, 2019
Esta investigación trata sobre los estándares de calidad y su incidencia en el desempeño docente de la educación general básica y bachillerato. Como muestra se escogió la Unidad Educativa Catalina Cadena Miranda, ubicado en el Cantón El Triunfo.
Adriana Olmedo Valencia   +1 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Sucesiones y la dimensión fractal [PDF]

open access: yes, 2012
A través de una serie de problemas, cuya solución nos sumerge en el mundo matemático de los procesos infinitos, en forma natural se llega a la idea de sucesión y límite de una sucesión. En algunos de los problemas planteados aparecen objetos geométricos,
Hernández, Luis
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Estudio de caso: dinámica y limitantes de la sustentabilidad en la agricultura familiar en la comunidad campesina San Francisco de Cayran, Huánuco- Perú (2017-2021)

open access: yesRevista de Investigación e Innovación Agropecuaria y de Recursos Naturales
La agricultura familiar (AF) a nivel global cumple roles económicos, ambientales y socioculturales, siendo fundamental conocer su estado de sustentabilidad y sus puntos críticos.
Henry Briceño-Yen
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

RESPONSABILIDAD SOCIAL EN PYMES DEL ÁREA METROPOLITANA DE MEDELLÍN, COLOMBIA // SOCIAL RESPONSIBILITY IN SMES IN THE METROPOLITAN AREA OF MEDELLÍN, COLOMBIA // RESPONSABILIDADE SOCIAL EM PEQUENAS EMPRESAS DA ÁREA METROPOLITANA DE MEDELLÍN, COLÔMBIA

open access: yesDimensión Empresarial, 2016
Este trabajo de investigación tuvo como objetivo indagar por los conocimientos, actitudes y prácticas sobre Responsabilidad Social Empresarial (RSE) en las pymes del sector aseo en el Área Metropolitana de Medellín.
Laura Marcela Giraldo-Cárdenas   +2 more
doaj   +1 more source

La dimensión religiosa del hombre [PDF]

open access: yes, 1949
Fil: Todolí, José.
Todolí, José
core  

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