Results 71 to 80 of about 38,865 (173)

Geographical influence area of the bartolome giacomotti primary health care center, Concepcion del Uruguay, Entre Rios [PDF]

open access: yes, 2014
El artículo realiza un análisis espacial de la cobertura del Centro de Atención Primaria de la Salud (CAPS) con el objetivo de analizar la accesibilidad al CAPS y conocer el alcance territorial del centro de salud, evaluar si los usuarios pertenecen a su
Curto, Susana Isabel   +2 more
core  

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

open access: yesAdvanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen   +7 more
wiley   +1 more source

Niveles de vida y diferencias rural-urbana de la estatura en los inicios del crecimiento económico español [PDF]

open access: yes, 2014
This paper examines the urban-rural differences of the height during the early stages of modern economic growth and industrialization in Spain. Its aim is to explore the extent of the urban penalty, and the changes of biological welfare in the cities and
Martínez-Carrión, José Miguel   +3 more
core  

Bioinspired Engineering of Streamlined Skeletal Interoception: Neural Bioprinted Piezoelectric Scaffolds for Neuro‐Vascularized Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This study develops neural bioprinted piezoelectric scaffolds which construct local “sensor‐effector” circuit, inspired by the skeletal interoception system. Upon US stimulation sensing and mechanoelectrical coupling by PLLA nanofibers, the incorporated DRG neurons effect through Ca2+ influx‐induced enhanced secretion and expression of CGRP.
Yingze Su   +18 more
wiley   +1 more source

Defect‐Rich 2D Layered Double Hydroxides Enhance Sonodynamic Antibacterial Therapy

open access: yesAdvanced Science, EarlyView.
This study develops defect‐rich ultrathin ZnCuW‐LDH nanosheets (DR‐ZnCuW‐LDH) via acid etching. DR‐ZnCuW‐LDH exhibits fourfold enhanced US‐triggered ROS production due to oxygen defects and electronic modulation, demonstrating potent antibacterial efficacy in vitro/vivo.
Qian Liu   +6 more
wiley   +1 more source

Investigación, innovación y transferencia en el sector del aceite de oliva en España. Un Análisis mediante paneles presenciales de expertos [PDF]

open access: yes, 2014
El trabajo tiene como primer objetivo obtener una visión consensuada de los problemas y prioridades de investigación, desarrollo, innovación y transferencia del sistema nacional de I+D+i (Investigación, Desarrollo e Innovación) sobre el sector oleícola
Coq Huelva, Daniel   +3 more
core  

Rethinking Power Solutions for Healthcare Wearables: From Point‐of‐Care and Episodic use to Continuous Monitoring and Therapeutic Platforms

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
This Perspective examines practical power solutions for wearable healthcare systems, highlighting the limits of standard batteries. It categorizes wearables into four domains—point‐of‐care diagnostics, episodic monitoring, continuous long‐term monitoring, and therapeutic platforms—and analyzes their power needs.
Seokheun Choi
wiley   +1 more source

Análisis de vulnerabilidad del Municipio de Cota Cundinamarca a través de una visión sistémica del territorio [PDF]

open access: yes, 2015
Trabajo de Investigación Científica y de Desarrollo TecnológicoEste documento consta del análisis de la vulnerabilidad del municipio de Cota, Cundinamarca, Colombia, a través de una visión sistémica del territorio y el cálculo del índice de ...
Montaño-Pinilla, Marisella   +1 more
core  

Identification of Exhaled Volatile Organic Compounds Biomarkers for Lung Cancer Under Data‐Limited Conditions Using Data Augmentation and Multi‐View Feature Selection

open access: yesAdvanced Intelligent Discovery, EarlyView.
This work introduces a novel framework for identifying non‐small cell lung cancer biomarkers from hundreds of volatile organic compounds in breath, analyzed via gas chromatography‐mass spectrometry. This method integrates generative data augmentation and multi‐view feature selection, providing a stable and accurate solution for biomarker discovery in ...
Guancheng Ren   +10 more
wiley   +1 more source

Más allá del individualismo: el tercer sector en el Perú [PDF]

open access: yes, 2002
Analiza el surgimiento y creciente visibilidad de las organizaciones privadas sin fines de lucro (OPSFL) en el Perú durante las dos últimas décadas. Las OPSFL poseen una lógica de operación diferente a la del Estado, que busca proporcionar bienestar ...
Cueva, Hanny   +3 more
core  

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