Results 201 to 210 of about 264,579 (261)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

How Extreme Is It Anyways?: An Empirical Investigation Into the Prevalence and Strength of Extreme Response Style. [PDF]

Educ Psychol Meas
Schoenmakers M, Tijmstra J, Vermunt JK, Bolsinova M.   +3 more
europepmc   +1 more source

Spatially Decoupling Heating and Evaporation for Convection‐Enhanced 3D Solar Evaporation With Continuous Salt Harvesting

Advanced Functional Materials, EarlyView.
An architecture‐enabled bottom‐heated 3D solar convective evaporator spatially decouples photothermal heating from evaporation, triggering natural convection that intensifies sidewall vapour removal and heat transfer. The system achieves significantly enhanced evaporation rates over 2D and conventional 3D designs while confining salt precipitation to ...
Xiaolong Ma, Yan Zhao, Yan Yan, Muhammad Amjad, Guice Yao, Hui Gao, Shudan Wei, Dongsheng Wen   +7 more
wiley   +1 more source

Nature connectedness framework for adolescents: an integrative review. [PDF]

Front Psychol
Yildirim G, Willison J, Bentley B.
europepmc   +1 more source

Twin Crystal Moiré Metasurfaces for Crossing Flat‐Band Transport

Advanced Functional Materials, EarlyView.
This study introduces twin crystal moiré metasurfaces, breaking in‐plane symmetry to enable reconfigurable acoustic wave manipulation. By adjusting the twin angle and interlayer twist angle, various combinations of hyperbolic, flat bands, and elliptic states can be synthesized in the system.
Shida Fan, Chenglin Han, Kuan He, Chadi Ellouzi, Yunlong Wang, Li‐Qun Chen, Jie Sun, Zhaodong Xu, Chen Shen, Tianzhi Yang   +9 more
wiley   +1 more source

Fractal dimension-based multi-focus image fusion via distance-weighted regional energy in curvelet domain. [PDF]

Sci Rep
Lv M, Jia Z, Le W, Li L, Ma H.
europepmc   +1 more source

Bioinspired Mechanically Robust Organic–Inorganic Hybridized Bio‐Adhesives With up to 50% Inorganic Components by Bi‐Continuous Phase Engineering

Advanced Functional Materials, EarlyView.
A robust plant protein adhesive was prepared by fabricating a bi‐continuous organic–inorganic hybrid structure. Compared with traditional organic–inorganic hybrid adhesives, the addition amount of inorganic phase is increased from 0.2%–3.0% to 50%, and the strength and toughness are increased by 6 and 121 times, respectively.
Zheng Liu, Wenlong Luo, Xu Yang, Xin Zhang, Yuru Zhu, Jingchao Li, Jianzhang Li, Jing Luo, Zhezhe Zhou, Pingan Song, Qiang Gao   +10 more
wiley   +1 more source

First evaluation framework based on the one welfare concept in extensive broiler rearing systems. [PDF]

Sci Rep
Rocchi L, Mattioli S, Collin A, Bonnefous C, Warin L, Tuyttens F, Thobe P, Re M, Castellini C.   +8 more
europepmc   +1 more source

Controlled Engineering of 2D Alkali‐Iron‐Chloride Compounds and Lateral Quantum Heterostructures Within Confined Graphene Nanoreactors

Advanced Functional Materials, EarlyView.
This work presents a programmable atomic engineering strategy for 2D materials using Å‐scale nanoreactors formed by bilayer graphene (BLG) intercalation. A new class of alkali‐iron‐chloride compounds, along with lateral heterostructures composed of monolayer alkali halides and iron chlorides, is revealed.
Haiming Sun, Qiunan Liu, Yung‐Chang Lin, Mahdi Ghorbani‐Asl, Hiroki Ago, Arkady V. Krasheninnikov, Kazu Suenaga   +6 more
wiley   +1 more source

Rapid 3D Measurement of Tire-Pavement True Contact Texture and Its Implications for Skid Resistance. [PDF]

Materials (Basel)
Mamat T, Cheng S, Xu L, Xiao S, He C.
europepmc   +1 more source